42 



Scientific Proceedings (55). 



Streptothrix organisms in the form of the typical pinhead- 

 sized granules were found in the sputum of all six cases reacting to 

 streptotricin. Two cases showed a positive reaction to both tests, 

 and in the sputum of one, both organisms were present in profusion; 

 in the other, only the streptothrix. All these cases reacting to the 

 streptotricin show the characteristic organism in good sputum 

 specimens. 



The reaction in the cases so far observed is a bright red hyper- 

 emic area from 7-10 mm. in diameter, a slight induration in the 

 center, but without any tendency to form the dense induration of 

 some of the tuberculin reactions. Examinations were recorded 24 

 and 36 to 48 hours after vaccination, but later in some cases where 

 there was quite a tendency to induration, lasting even a week. 

 Observations are now being made on other cases and on presumably 

 normal people to determine the range and reliability of the reaction. 



24 (841) 



Further note on the influence of cholesterol on the growth of 



tumors. 



By Theo. C. Burnett (by invitation). 



[From the Rudolph Spreckels Physiological Laboratory of the Uni- 

 versity of California.] 



In previous papers it has been shown by Robertson and the 

 writer, that cholesterol accelerates the growth of carcinoma in 

 rats, and also, in view of the recent work of Wacker and of Ellis 

 and Gardner, it may be a factor in the incidence of cancer. 1 In 

 our original experiments the cholesterol was injected into, or 

 around the tumor, and the criticism has been made, and justly 

 too, we think, that the increase in the growth of the tumor might 

 be due to the mechanical irritation of the injections, although we 

 had previously controlled this possibility by injections of a 

 balanced salt solution. We determined to test this matter further 

 by making the injections on the opposite side of the body to that 

 of the inoculations, and it has been the privilege of the writer to 

 carry on these experiments in the absence of Robertson on sab- 



1 Robertson and Burnett, Jour. Exp. Med., Vol. 17, No. 3, 1913, p. 344; Proc, 

 Soc. Exp. Biol, and Med., Vol. 10, 1913, p. 140. 



