76 Scientific Proceedings (57). 



injected alone intraperitoneally either did not kill or whenever 

 it did, the peritoneum was found filled with free typhoid bacilli. 

 In some of the experiments the bacteria found in the peritoneal 

 cavities of dead guinea-pigs appeared larger than organisms of the 

 same strain taken from agar, having some of the characteristics 

 of which Bail speaks as "Tierische bazillen." In one of our 

 experiments, so far, they have shown resistance to agglutination. 



We have carried out several experiments to determine whether 

 or not this "aggressin" action is specific but owing to the diffi- 

 culties of entirely ridding the anaphylatoxin of the bacteria with 

 which it was produced we have been prevented from coming to 

 definite conclusions. Filtration through Berkefeld candles in a 

 few cases in which it was tried seemed to render the anaphylatoxin 

 harmless when intravenously injected. From a number of experi- 

 ments carried out with the Staphylococcus aureus and the Bacillus 

 prodigiosus, however, we are inclined to believe that the action is 

 not specific. 



It seems not unlikely to us that the aggressins with which 

 Bail worked were rather of the nature of "anaphylatoxin" and 

 that the invasive properties of bacteria may well be gradually 

 enhanced in the animal body as contact with the serum induces 

 the formation of these substances. We abstain from further 

 theoretical expansion of the ideas suggested by these experiments 

 at present. 



45 (862) 



(a) The lipolytic activities of human duodenal contents, (b) The 

 separation of the castor bean lipases. 



By K. George Falk. 



[From the Harriman Research Laboratory, Roosevelt Hospital.] 



Some years ago, Loevenhart 1 showed that extracts of the pan- 

 creas and of the liver of various animals contained different lipases. 

 The pancreas extracts exerted greater lipolytic action under com- 

 parable conditions toward complex esters such as glyceryl tri- 

 acetate, and the liver extracts showed greater action toward simple 

 esters such as ethyl butyrate. 



1 J. Biol. Chem., 2, 429 (1907). 



