Effect of Internal Secretions upon Pancreas. 99 



In the presence of much chromlipin (lipochrome) this method 

 does not work so well as it requires from 12 to 24 hours for the 

 insoluble lipins to separate out and as a rule the precipitate goes 

 to the bottom of the container instead of rising to the surface. It 

 appears from this observation that the presence of chromlipin in 

 some way changes the physico-chemical conditions of the asso- 

 ciated lipins. 



59 (876) 



Note on the effect of the internal secretions upon the volume of 



the pancreas. 



By Isaac Ott, M.D., and John C. Scott, M.D. 



[From the Laboratory of the Medico-Chirurgical College of 

 Philadelphia.] 



We have studied the action of infusions of the various dried 

 glands upon the volume of the pancreas. The animals used were 

 etherized cats. The injections were made per jugular. The 

 volume of the pancreas was registered with a modified piston 

 recorder. 



Infundibulin (pituitrin) causes a marked increase in the volume 

 of the pancreas. Adrenalin produces a decrease in volume for a 

 short time and then an increase. The pineal gland infusion in- 

 creases the volume. Infusion of thyroid momentarily decreases 

 and then increases the volume. Iodothyrin also increases the 

 volume. Thymus does the same. 



Secretin depresses blood-pressure for a short time and increases 

 the volume of the pancreas to a marked extent. 



Infusion of pancreas decreases the volume for a moment and 

 then increases the volume of the pancreas. The renal cortex 

 decreases the blood-pressure for a moment, but increases the 

 volume of the pancreas to a marked extent. 



Prostatic infusion had no effect on pancreatic volume. Ton- 

 sillar infusion lowered blood-pressure and slightly increased volume 

 of pancreas. 



Mammary gland infusion decreased blood-pressure for a short 

 time but caused a marked increase in pancreatic volume. 



