Il8 



Scientific Proceedings (58). 



carbonate, sodium citrate, sulphuric acid, neutral sulphur and 

 sodium hydroxide have been given in the diet of maize and wheat 

 for periods of one, two and three months. One hundred and 

 ten fowls have been used. No detectable inhibition of the para- 

 thyroid overgrowth could be detected in the fowls given magnesium 

 carbonate, strontium carbonate, sulphuric acid, neutral sulphur, 

 sodium citrate or sodium hydroxide, — the growth being as marked 

 as in the controls. On the other hand, those given sulphuric acid 

 and neutral sulphur had more marked parathyroid enlargements 

 and softening of the bones than those given the other chemical 

 substances or the controls. In those fowls which had received 

 calcium there was uniformly less parathyroid overgrowth ; in those 

 given calcium hydroxide and calcium carbonate it was barely 

 detectable ; while in those given calcium lactate there was moder- 

 ate enlargement. No differences ascribable to sex could be deter- 

 mined. 



These observations suggest: (a) that the parathyroids of birds 

 are more susceptible to overgrowth than those of mammals; (b) 

 that calcium offers some protection against overgrowth; and (c) 

 that the parathyroids (as MacCallum has suggested) are intimately 

 associated with the function of calcium in the complex of body 

 metabolism and nutrition. 



74 (891) 



Liver necroses associated with Streptococcus infection. 



By Oskar Klotz and May E. Bothwell. 



[From the Pathological Laboratories, University of Pittsburgh, 

 Pittsburgh, Pa.] 



In a series of experiments upon rabbits fo determine the tissue 

 reactions to the infection by the Streptococcus viridans and having 

 special reference to the heart, arteries, and kidneys, several 

 sporadic examples of necrosis of the liver were encountered. Liv- 

 ing cultures of Streptococcus fecalis, Streptococcus mitis, and 

 Streptococcus salivarius were used. Repeated inoculations, from 

 three to five, had been made at intervals of four days. 



The earliest necroses appeared in eleven days and consisted 



