152 



Scientific Proceedings (59). 



through drying the same fundamentally as laking by hypertonic 

 solutions? Brahmachari 1 suggests that hypertonic solutions of 

 sodium chloride lake by uniting with some cellular constituent 

 and thus alter its normal properties. If this is true, it would 

 seem that such union is at least of a doubtful chemical character; 

 for a number of inorganic salts as well as cane sugar and glycerine 

 in hypertonic solution may cause laking. 



It is conceivable that the abstraction of sufficient water from 

 the discs in any manner as by evaporation or by hypertonic 

 solutions or by freezing, may so alter the molecular arrangement 

 of the essential structures that it is not possible for them sub- 

 sequently to imbibe or otherwise take up water and regain their 

 normal properties, — hence laking. 



94 (9") 



The schizogony in the life-cycle of Sarcocystis muris. 

 By Rh. Erdmann. 



[From the Osborn Zoological Laboratory, Yale University.] 



The first period of the life cycle of Sarcocystis muris extends 

 from the date of infection to the entrance of the unicellular 

 parasite into the muscular tissue of the host (20 to 30 days). 2 

 In my former publications I could only describe from this period 

 some large ameboid forms found in the walls of the intestine and 

 in the lymph vessels of experimentally infected mice. 3 



My present investigation shows the appearance of small 

 ameboid and schizogony forms six days after infection. These 

 stages were discovered after feeding sarcosporidia to young mice 

 nourished with milk from birth to the end of the experiments. 

 These small schizogony forms (0.3 to 0.4 ju) consist of a tiny proto- 

 plasmic body with a caryosome-nucleus, and arise from smaller 

 ameboid organisms which show typical schizogony. 



1 Bio-Chem. Jr., 1909, IV, 59. 



'Erdmann, "Die Entwicklung der Sarcocystis muris in der Muskulatur," 

 Sitzungsberichte der Gesellschaft Naturforschender Freunde, 1910, p. 399. 



* Ibidem, p. 382. Also cf. Erdmann, "Beitrage zur Morphologie und Entwicke- 

 lungsgeschichte des Hammelsarkosporids in der Maus," Cenlrb.fiir Bakt. und Parasitk., 

 1910, Bd. 53, Abt. I Orig., p. 515. 



