30 



Scientific Proceedings (109). 



in the wall of a single Cysticercus cyst, one of 30 to 50 present in 

 this organ. Each of the involved cysts contained a worm about 

 20 cm. long, only one of which was living. Three of the tumors 

 had metastasized freely into the peritoneal tissues. In each of 

 two of the animals early and probably independent malignant 

 changes had occurred in the walls of other cysts in the liver. 

 Histologically, the tumors were sarcomata of either the spindle- 

 cell or polymorphous-cell type. The transplantation of two of 

 them into young rats resulted in 92 and 46 per cent, respectively 

 of successful inoculations. The other two were not transplanted. 



Complete data on a fifth ^at which bore a tumor is lacking due 

 to the loss of the liver through partial evisceration of the animal 

 by his cage mates. The peritoneal tissues were, however, studded 

 with tumor nodules which histologically proved to be spindle-cell 

 sarcoma. In all probability these nodules were metastases from 

 a primary growth of the liver. 



19 (1601) 



Further studies on intestinal implantation of bacillus acidophilus. 



By Harry A. Cheplin and Leo F. Rettger. 



[From the Sheffield Laboratory of Bacteriology, Yale University, New 



Haven, Conn.] 



The more recent observations on transformation of the intesti- 

 nal flora in man have fully confirmed the earlier conclusions, which 

 are briefly summed up as follows. The daily administration of 

 150-300 grams of lactose or dextrin to adults will, with few excep- 

 tions, bring about a marked change in the character of the flora 

 in which the usual mixed types of bacteria give way to Bacillus 

 acidophilus of Moro, which is a normal intestinal organism, but 

 which is present in the intestine after early infancy in relatively 

 small numbers only. In some instances 350-400 grams of the 

 carbohydrates are required. The same results may be brought 

 about with 150-300 cubic centimeters of a whey broth culture 

 of B. acidophilus and with 500-1,000 c.c. of B. acidophilus milk, 

 as well as with smaller amounts of the milk in combination with 

 100 grams of either lactose or dextrin. 



