Anemia of Medulla Oblongata. 



155 



some cases it seemed to diminish it. This was perhaps due to 

 secondary factors (pressure of the distended skin which injures 

 the graft or makes its sterile introduction into the wound more 

 difficult) ; in a number of cases the growth of the transplant was 

 equally good in pregnant and non-pregnant animals. 



Localized infection of the graft with ordinary bacteria does 

 not call forth a lymphocytic reaction in case of autotransplantation 

 and it does not prevent its appearance in the case of homoiotrans- 

 plantation. It may, however, interfere with the other variable 

 factors and call forth a greater production of fibrous tissue. 

 This may be associated with retardation in the organization of 

 the necrotic center and with partial destruction of the parenchyma. 

 Sex does not influence the four variables in the case of thyroid 

 transplantation in the guinea pig. Whether the inferiority in 

 results obtained after transplantation from child to mother 

 which we found previously, is due to the action of a constitutional or 

 of an extraneous factor remains still to be determined. 



75 (1657) 



The vasomotor response in anemia of the medulla oblongata: 



(1) The splanchnic vaso-constrictor fibers. 



(2) The relation of the splanchnic constrictor fibers to the secre- 

 tion of adrenalin. 



By CORA S. WINKIN. 



[From the Department of Physiology of Columbia University.] 



The experiments here reported deal with a series of studies on 

 the analysis of the vasomotor response in asphyxia. The first of 

 this series had particular reference to the part played by the 

 splanchnic constrictor fibers in the response. The second series 

 was concerned with the relation of the activity of these fibers to 

 the secretion of adrenalin. The procedure throughout was the 

 infliction of a complete but temporary anemia on the entire 

 brain, according to the technique of Stewart et al., 1 by clamping off 



' 1 Stewart, Guthrie, Burns and Pike, Journ. Exp. Med., 1906, viii, 289. 



