212 



Scientific Proceedings (115). 



After a preliminary period of observation of about one week, 

 0.6 gm. of arsphenamin (using ampules of the same lot number and 

 produced at the Dermatological Research Institute) was injected 

 intravenously in 120 c.c. of distilled water by means of a gravity 

 apparatus. Details of the analyses are given in Table I. 



TABLE I. 



Showing Chemical Changes in the Blood of Syphilitics during Arsphenamin 



Treatment. 



Patient I: T. M., Male, Age 38— Optic Atrophy. 



Date. 



Total Non-Protein 

 Nitrogen. 



Urea 



Nitrogen. 



Sugar. 



Remarks. 



10-25-20 



24.2 



II. I 



85.I 





10-26-20 



30.0 



13-2 



100.0 



2 



10-26-20 



32.9 



13-2 



123.8 



yi 



IO-27-20 



36.8 



20.6 



130-2 



V 



10-29-20 



31.4 



17.2 



133.8 





II- 2-20 



39-5 



14.3 



115.6 





II- 4-20 



33-4 



14.9 



103.9 





II- 8-20 



34-3 



22.4 



131-6 





II- 9-20 



23.2 



8.1 



133-3 



3 



II- 9-20 



28.4 



9.4 



129.9 



D3 



II-IO-20 



44-3 



14.8 



121. 2 





II-I3-20 



34-5 



11.3 



137-9 





II-I6-20 



32.6 



12.6 



137-9 





II-I8-20 



310 



12.4 



139-9 





11-22-20 



32.4 



18.1 



121.6 





11-23-20 



34-8 



16.9 



116.3 



V 1 



11-24-20 



38.2 



18.3 



117.6 





II-20-20 



30.3 



135 



108. 1 





Patient II: M. J., Male, Age 28 — Optic Atrophy. 



1-19-21 



33-5 



II.4 



935 





1-20-2 I 



32.1 



II.4 



88.3 





1-2 1-2 I 



32.6 



11. 7 



in. 4 





1-25-2 I 



30-7 



12.2 



75-5 



s 



1-25-2 I 



32.8 



15-5 



153-8 



V3 



1-27-2 I 



31-5 



11.3 



1130 





I-28-2I 



31-5 



12.6 



89.9 





I-3I-2I 



30.7 



14.2 



137-9 





2- 2-21 



38.8 



18.6 



96.4 



G 



2- 4-21 



35-8 



17-5 



119. 0 





2- 7-21 



30.9 



14-3 



107-5 





1 All figures are given in milligrams per 100 c.c. of blood. 



2 Injection immediately after sample was drawn. 



» Patient received an intravenous injection of 0.6 g. arsphenamin 3 hours before 

 this sample of blood was drawn. 



V = "reaction" — patient vomited. 



D = severe reaction with vomiting, diarrhea and pain in the legs. 

 G = gastric crisis. C = slight reaction — chills. 



