272 



Scientific Proceedings (116). 



Summary of Results. 

 Ca Expressed as mg. per 100 c.c. 



Normal Human. 



Normal Dog. 



Human Rickets. 



Dog Tetany. 





Per 





Per 





Per 





Per 



Serum 



Cent. 



Serum 



Cent. 



Serum 



Cent. 



Serum 



Cent. 



Ca. 



Diffusible 



Ca. 



Diffusible 



Ca. 



Diffusible 



Ca. 



Diffusible 





Ca, %. 





Ca, %. 





Ca, %. 





Ca, %. 



10.5 



65 



10.9 



68 



9.0 



68 



6.3 



62 



11. 1 



67 



11. 1 



69 



7-6 



63 



6.1 



63 



10.5 



67 



10.7 



60 







6.7 



66 



10.3 



68 



10.6 



61 











11. 0 



72 



10.2 



69 











10.4 



70 















These observations indicate that there is no change in the 

 proportion of diffusible serum calcium in human rickets, or in 

 experimental dog tetany. 



138 (1720) 



The relation of acid base equilibrium in the body to excretion of 

 phosphorus and calcium. 



By T. F. ZUCKER. 



[From the Department of Pathology, College of Physicians 

 and Surgeons, Columbia University.] 



The relation of the acid base equilibrium in the animal body 

 to calcium and phosphorus metabolism has been studied by a 

 number of workers. 1 The significance of variation in the acid 

 base equilibrium is undoubted, but considerable confusion is en- 

 countered, when an attempt is made to correlate the available 

 results. A good many of the experiments have been done on small 



1 Gerhard and Schlesinger, Arch. exp. Path. u. Pharm., 1899, xlii, 83. 

 Fitz, Alsberg and Henderson, Am. Jour. Phys., 1907, xviii, 113. 

 Schabod, Arch. f. Kinderh., 1909, Hi, 47; 1910, liii, 381; 191 1, liv, 83. 

 Graustrom, Ztschr. f. physiol. Chemie, 1908, lviii, 195. 

 Goto, Jour. Biol. Chem., 1918, xxxvi, 355. 

 Givens, Jour. Biol. Chem., 1917. xxxi, 421. 

 Ruedel, Arch. f. exp. Path. u. Pharm., 1894, xxxiii, 79. 

 Dubois and Stolte, Jahrb. Kinderh., 1913, xxxiii, 21. 

 Nelson and Williams, Jour. Biol. Chem., 1917. xxviii, 231. 



