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Scientific Proceedings (116). 



gms. of pancreatic tissue was removed with no change in the 

 urinary findings. On February 9, blood sugar was 86 mgms. On 

 this day 150 gms. glucose were introduced by the stomach tube. 

 Tests for urinary sugar remained negative. On May 9, rest of 

 the pancreas, amounting to 10 gms. was removed. Urine con- 

 tinued negative for sugar until May 14, when intestines prolapsed 

 through wound, followed by death next day. Autopsy revealed 

 complete absence of pancreatic tissue. His blood sugar was 66 

 mgms. before the last pancreatectomy and his weight 15.9 kilo. 



Dog No. 106, male, weight 7.52 kilo., complete pancreatectomy 

 on March 2, 1921; weight of removed pancreas being 18.2 gms. 

 Urine positive for sugar, beginning day following operation in 

 amounts varying between 5 and 6 per cent. On March 5, both 

 superior and inferior thyroid arteries were ligated. He continued 

 to have sugar in decreasing amounts until March 8, when the 

 urine became negative for sugar. Urine continued to be negative 

 for sugar until March 19, when distemper developed followed by 

 death the next day. 



Blood sugar findings were as follows: 



March 2, before operation 76 mgms. 



Autopsy revealed lobular pneumonia involving all the lobes. 

 Complete absence of pancreatic tissue. 



Dog No. in, male, weight 6.66 kilo., complete pancreatectomy 

 done on April 4, 1921. Weight of removed specimen 17 grams. 

 Blood sugar prior to operation 78 mgms. Urine positive for 

 sugar on day following the operation. Blood sugar on April 10, 

 200 mgms. On this day the right superior and inferior thyroid 

 arteries were ligated. Urine continued positive for sugar until 

 April 17, when the thyroid arteries on the left side were ligated. 

 Blood sugar on this day was 244 mgms. No change in the urinary 

 sugar until April 19, on which day death occurred from tetany. 

 Weight before death 5.66 kilos. 



Diet of all the animals was liberal consisting of meat, bread 

 and water. All wounds healed per primam. Further experiments 

 along these lines are in progress. 



4, after pancreatectomy 



5, after ligation 



6 



250 

 192 

 90 

 50 



7 



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