Lactic Acid in Blood of Dogs in Exercise. 



307 



Table II. 



The Effect of Moderate Exercise, Long Continued, on the Concentration 

 of Lactic Acid in the Blood of Dogs. 







Distance 



Rate 



Lactic Acid in Mgm./ioo c.c. 



Dog. 



Date. 



in 



in 



Before 



After 







Miles. 



Miles/hr. 



Exercise. 



Exercise. 



A 





11. 0 



4.9 



4.9 



2.9 









February 15, 192 1 .... 



27.0 



4-5 



7.8 



6.2 



B 



February 9, 192 1 



10.8 



5-o 



12.4 



6.3 





May 3, 1921 



5-2 



5-2 



24.2 



16.7 



C 



January 30, 1921 



13-7 



5-5 



13-4 



9.6 









February 24, 192 1 .... 



22.8 



4.6 



132 



7-8 



159 (1741) 



A case of metastatic calcification associated with chronic nephritis 

 and hyperplasia of the parathyroids. 



By ROGER S. HUBBARD and JOHN A. WENTWORTH. 



[From the Clifton Springs Sanitarium, N. Y.] 



The case was one of severe chronic nephritis in a man of twenty 

 years. About the larger joints of the upper extremities and about 

 the feet were many fluctuant tumor masses of various size, and 

 distributed along the course of many of the peripheral arteries 

 were innumerable bead-like nodules which could be felt, while 

 x-ray plates showed extensive calcification of the peripheral arteries 

 and large irregular deposits about the joints. 



The aspirated contents of one of the tumors was found to be 

 a thick, creamy fluid simulating pus in the gross, containing 

 amorphous material without cells and a suspension of calcium 

 phosphate of 30 per cent. Otherwise the analysis of the fluid 

 resembled normal synovia. 



A peripheral artery bearing the nodules was excised from the 

 leg and was found to be stiff, very tortuous, and to have numerous 

 small yellow and white deposits of calcium in the wall. Mi- 

 croscopically the media was largely replaced by calcium salts, 

 the intima was much thickened, and in places there was little 

 lumen. 



