196 



CHOLERA 



first time applied in a prevalent epidemic, and very 

 weak doses of a relatively weak vaccine were used. 

 . . . Far higher results have been obtained by an 

 application of stronger doses. In the bustees 

 situated round the tanks in Calcutta, where cholera 

 exists in a permanent state, the disease occurred in 

 36 houses with inoculated people. In each of 

 these houses there was one part of the family 

 inoculated and another not. The observations were 

 continued for 459 days, with the following 

 results : — 



During the first period of 5 days, subsequent to 

 the inoculation with first vaccine, cholera occurred 

 in 8 houses. 



75 non-inoculated had 5 cases, with 3 deaths. 

 52 inoculated had 3 cases, with 3 deaths. 



During the second period of 5 days, subsequent 

 to the second inoculation, cholera occurred in 2 

 houses. 



8 non-inoculated had 2 cases, with 2 deaths. 

 17 inoculated had no cases. 



After the 10 days necessary for the preventive 

 treatment had expired, and up to the ^$<fth day, the 

 disease visited 26 houses. 



263 non-inoculated had 38 cases, zvith 34 

 deaths. 



137 inoculated had 1 case, with 1 death, in a 

 child that had not been brought up for the 

 second inoculation. " 



