IX 



TYPHOID FEVER. MALTA FEVER 



TYPHOID FEVER 



HTHE names of Klebs, Eberth, and Koch, are 

 associated with the discovery, in 1 880-81, of 

 the bacillus of enteric fever, bacillus typhosus ; and 

 it was obtained in pure culture by Gaffky in 1884. 

 It has been studied from every point of view, in 

 man and in animals ; in the blood, tissues, and 

 excretions ; in earth, air, water, milk, and food ; in 

 its distribution, methods of growth, and chemical 

 products. Especially, the study of its chemical 

 products has been directed toward (1) immunisation 

 against the disease, (2) bacteriological diagnosis of 

 the disease at an early stage. 



The date of the first protective inoculations 

 against typhoid is July- August 1896: they were 

 made at Netley Hospital, by Professor Wright and 

 Surgeon- Major Semple. The first inoculations in 

 Germany, made by Pfeiffer and Kolle, were published 

 two months later. The story of these famous 

 Netley inoculations is told in the British Medical 



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