SANARELLI 



281 



February 1898, yellow fever broke out in the jail at 

 San Carlos : — 



" La premiere victime fut un condamne, qui 

 vivait avec tous les autres dans une salle ou les 

 conditions hygieniques etaient assez mauvaises. Le 

 lendemain, la sentinelle, qui etait en rapport con- 

 tinuel avec la salle des condamnes, tombait malade. 

 Quelques jours apres, un autre condamne suivait le 

 sort du premier, et bientot un quatrieme cas, mortel 

 aussi, finit par signaler la prison comme un nouveau 

 foyer d'infection qui venait s'allumer au centre d'un 

 quartier de la ville encore reste indemne. 



" Si on avait abandonne la chose a. elle-meme, 

 on aurait vu se produire le meme spectacle qu'avaient 

 fourni, dans les conditions identiques, pendant les 

 dernieres epiderries, les prisons de Rio-Claro, de 



Limeira, et d'autres villes de l'Etat de Saint-Paul." 



Every prisoner, except one who had already had 

 the fever, was therefore given the preventive treat- 

 ment. At once the outbreak stopped ; no more 

 cases occurred, though only a weak serum was used, 

 though the state of the prison and its occupants was 

 unhealthy, though the fever, two months later, was 

 still raging, round the prison, in the town. 



That Sanarelli did, as a matter of fact, obtain 

 these good results with his serum treatment, is not 

 denied : but some more recent authorities take the 

 bacillus icteroides to be a secondary invader in the 

 disease, and not the specific organism of the disease. 



In October 1900, the United States Commis- 

 sion on Yellow Fever published a preliminary 

 report on 1 1 cases of mosquito-inoculation. Of 



