306 



THE ACTION OF DRUGS 



history of anaesthesia is to be found in the 

 Practitioner, October 1896. 



It is sometimes said that the men who make 

 experiments on animals ought to make them on 

 themselves. But they do, hundreds of them, and 

 suffer for it : Heaven knows the list is long enough 

 — the discoverers of anaethesia, Hunter, Garre, 

 Koch, Klein, Moor, Haffkine, Grassi, Boche- 

 fontaine, Quesada, Sanarelli, Pettenkofer — these and 

 many more, here or abroad, have done it, as part of 

 the day's work ; and some — by accidental infection, 

 like Chabry and Villa, or by deliberate self-inocula- 

 tion, like Carrion — have been killed : — 



" Dr Angelo Knorr, Privat-docent in the Veteri- 

 nary School of Munich, died on 22nd February from 

 acute glanders, contracted in the course of an 

 experimental research on mallein. Helmann, the 

 Russian investigator who discovered mallein, himself 

 fell a victim to accidental inoculation of the glanders 

 virus. Some time afterwards another Russian, 

 Protopopow, died of glanders contracted in a French 

 laboratory. An Austrian physician, Dr Koffman- 

 Wellenhof, died of the same disease, contracted in 

 the Institute of Hygiene at Vienna. On 17th 

 January of the present year Dr Guiseppe Bosso, of 

 the University of Turin, died of infection contracted 

 in the course of cultivations of tubercle-bacilli made 

 in his laboratory. Not long before, Dr Lola, 

 assistant in the maternity department of the Czech 

 University Hospital of Prague, died of tetanus 

 caused by an experimental inoculation made on 

 himself. Some fourteen or fifteen years ago, a 

 medical student of Lima proved that 'verruga 

 Peruana ' is an infectious disease by inoculating 



