Mosquitoes and Malaria 1 1 1 



and the waste products that have been stored away 

 within the cell are liberated into the blood-plasm. 



These spores are round or somewhat amoeboid 

 and are carried in the blood for a short time. Very 

 soon, however, each one attacks a new red cor- 

 puscle and the process of feeding, growth and 

 spore-formation continues, taking exactly the same 

 time for development as in the first generation, so 

 every forty-eight hours in the case of the vivax, and 

 every seventy-two hours in the case of the malarice 

 a new lot of these spores and the accompanying 

 waste products are thrown out into the blood. 

 Thus in a very short time many generations of 

 this parasite occur and thousands or hundreds of 

 thousands of the red-blood corpuscles are destroyed, 

 leaving the patient weak and anemic. It will be 

 seen, too, that the recurrence of the chills and fevers 

 is simultaneous with the escaping of the parasites 

 from the blood-corpuscles, together with the waste 

 products of their metabolism. 



These waste products are poisonous, and it is be- 

 lieved that this great amount of poison poured into 

 the blood at one time causes the regular recurring 

 crisis. Zoologists well know that this process of 

 asexual reproduction, i. e., reproduction without 

 any conjugation of two different cells, cannot go on 

 indefinitely, and those who were studying the life- 



