474 



TELOSPORIDIA 



EimeriaA. Schneider, 1875. 



Tetrasporocy slides with the formation of an oocyst after fecundation ; sporo- 

 blasts in the form of a pyramid; spores globular or oval, provided with a 

 micropyle. 



Eimeria stiedse Lindemann, 1865. 



Synonyms. — Psorospevmium cuniculi Rivolta, 1878; Coccidium oviforme 

 Leuckart, 1879; C. perforans Leuckart; Pfeifferia princeps Labbe, 1896. 



This is the common species found in the liver of rabbits. The spores 

 swallowed by the rabbit are opened by the action of the acid of the gastric 

 juice, and the sporozoites set free ascend the bile-duct, and pass into the cells 

 lining the sm.ail bile-ducts. Here they propagate vigorously by schizogony, 

 causing proliferation of the epithelium and connective tissue of the ducts, so 

 that thick- walled nodules, more or less isolated and containing caseous material 

 (consisting of detritus, pus, epithelial cells, and coccidia), are formed. The 

 inflammation may be severe enough to kill the rabbit. 



Sporogony proceeds with the formation of macrogametocytes with macro- 

 gametes, and the microgametoc3^tes with microgametes, which conjugate and 

 form zygote, sporoblast, spores, and sporozoites {vide Coccidiosisin man, infra). 



Family Polysporocystid^ Leger. 



Comprises a large number of genera: Adelea A. Schneider, 1875 (dizoic) ; 

 Klossia (tetrazoic) A. Schneider, 1875; Minchinia Labbe, 1896; Klossiella 

 Smith and Johnstone, ig02 ; Bawonsia [monozoic) ; Benedenia (trizoic). 



Coccidiosis in Man. 



The utmost confusion has existed as to this infection of man, 

 but now, thanks to the labours of Dobell, whose Writings we have 

 followed, the subject is more defined. 



In 1841 Johannes Miiller introduced the name ' psorosperms ' for 

 the spores of the myxosporidia, and as the coccidia were believed to 

 resemble these bodies, they were called ' oviform psorosperms ' 

 until Leuckart in 1879 gave them the name coccidium. The various 

 diseases and cases rightly or wrongly called coccidiosis at any time 

 in man may be considered as follows : — 



Diseases now known not to be Coccidiosis. — These are (i) a form 

 of blastomycosis (granuloma coccidoides); (2) rhinosporidiosis ; 

 (3) Darier's disease; (4) molluscum contagiosum. 



Cases wrongly diagnosed as Coccidiosis. — These are the cases 

 described by Virchow (i860), Rivolta (1873 and 1878), Grassi (1879), 

 Podwyssoki (1889), Giles (1890), Jurgens (1895), Quincke (1899), 

 Thomas (1899), Grunow (1901), and probably by Kiinstler and 

 Pitres (1884). 



Cases correctly recognized as Coccidiosis. — Dobell considers that 

 over seventy cases, mostly from the Near East, have recently 

 been recognized as coccidiosis. The earlier cases are:— 



Hepatic. — Grubler in Paris (1858), Dressier in Prague (recorded 

 by Leuckart )in 1863), Sattler in Vienna (recorded by Leuckart in 

 1879), Perls in Giessen (recorded by Leuckart in 1879); Perls and 

 von Sommeringf?) (recorded by Leuckart in 1879), and Silcoqk in 

 London (1890). 



