UMMOSPORlDlA 



477 



in length, and his drawings show four oocysts. The third case was 

 discovered by Sattler of Vienna in a pathological preparation. It 

 showed a dilated bile-duct with greatly proliferated epithelium 

 and coccidia. 



The fourth case is by Perls; it was from a preparation made by 

 von Sommering, and is said by Leuckart to have contained coccidia. 



The fifth and last case is that described by Silcock in 1890 at 

 St. Mary's Hospital, London. A woman aged fifty had enlargement 

 of the liver and spleen, with fever and slight diarrhoea. At the 

 post-mortem the liver was much enlarged and showed a number of 

 caseous foci. The ileum contained six papule-like elevations 

 surrounded by an inflammatory zone, and the large intestine had 

 deeply congested patches of mucosa. 



In the caseous nodules were agglomerations of small oval, egg- 

 like bodies, with granular contents and a Well-marked capsule, and 

 Were considered to be identical with Leuckart 's coccidia. They were 

 kept in Water, and psorosperms freely developed. He considered 

 them to be Cocci dium oviforme, and to be present in the spleen, 

 but does not state anything definite as to the intestine. 



In all, therefore, up to 1918, five cases have been recorded. 



Dobell does not consider this parasite to be Eimeria stiedce, 

 judging from Dressier 's drawings. 



Gubler's case Was considered to be a hydatid cyst. Dobell's 

 conclusions are that there is a coccidial parasite which very rarely 

 occurs in the human liver, and resembles E. stiedce, but is consider- 

 ably smaller and is probably a distinct species, though perhaps 

 belonging to the same genus. 



Distribution. — Europe. 



Pathogenicity. — It causes cyst-like swellings of the liver, with 

 enlargement of that organ. 



ORDER III. H^MOSPORIDIA Doflein, 1901. 

 Synonym.— HcBMOcytozoa Mesnil, 1915. 



Definition. — 'Telosporidia, Coccidiomorpha without resistant spores 

 in the sporocysts and with the trophozoite stage intracellular. 

 With alternations of generation, schizogony in a vertebrate and 

 sporogony in a blood-sucking arthropod or leech. 



Remarks. — -Mesnil considers that the family Hsemogregarinidse 

 is related to Leger's Adeleidea division of the Coccidiidea, and the 

 Plasmodidse to the Eimeridea division, and that they should find 

 their places in that group. He considers that the genus Leucocyto- 

 zoon should come into the Hsemosporidia, and that the Piroplas- 

 midae require more study in the invertebrate before being classified. 

 There is no doubt that Haemosporidia is merely a temporary order 

 in which to place forms pending a fuller classification, which will 

 ^probably be on the lines indicated by Mesnil. 



Classification. — 'The following families may be temporarily placed 

 in this order for convenience, and can be differentiated as follows :— 



