hMMOGREGA RiNIDJS 



470 



traced. A danger is to mistake Crithidia pulicis of the flea for a developmental 

 stage of the H.jaculi. 



In 1905 Christophers discovered H. gerbilli in the Indian field -rat [Gerbillus 

 indicus), and traced its schizogony and later cyst-formation in a louse 

 (HcBwiatopinus stephensi) ; but he did not observe conjugation, nor did he 

 reinfect rats from the louse, and finally in 1907 he appears to think it probable 

 that the cysts he described may have nothing to do with the haemogregarine. 



Fig, 148. — Life-Cycle of HcBmogvegavina muris Balfour. 

 (After Miller.) 



1,2, Free sporozoites in the intestine of the rat penetrating the villus and 

 entering the blood; 3, entering the liver cells; 4-8, schizogony in the liver; 

 9, merozoite about to reinfect a liver cell; 10- 11, merozoite infecting a white 

 blood cell; 12, free vermicules in the stomach of the louse; 13, conjugation; 

 14, the zygote; 15, ookinete in the stomach; 16, ookinete in the wall of 

 the stomach; 17, ookinete; 18-19, oocyst; 20, sporoblasts appearing; 21, early 

 sporoblasts; 22, sporoblasts; 23, late sporoblasts; 24, formation of sporozoites. 



In 1906 Adie discovered a haemogregarine in Epimys rattus, Balfour one in 

 E. noYvegicus, Christophers another in Felis domestica, Patton another in 

 Funambulus pennantii. 



In 1907 Christophers traced the sporogony of H. cams in Rhipicephalus 

 sanguineus. In 1908 Miller contributes a most valuable paper on H. fmiris 

 Balfour, 1905, under the term Hepatozoon perniciosum Miller, 1908, in which he 



