PLASMODIUM 



and female pronuclei fusing to form a synkaryon, and the resulting 

 zygote is called an ookinete. This zygote elongates, and its anterior 

 extremity, which is more or less clear of hsemozoin, becomes pointed; 

 the nucleus lies in the middle, and the posterior end contains most 

 of the pigment, which may be largely cast off or may be retained. 



It now pierces the epithelium of the mosquito's stomach, below 

 which it comes to rest, and forms a thin cyst-wall, and is called the 

 oocyst. This now grows rapidly, and its nucleus divides into a large 



Fig. 169. — Diagram of the Life-Cycle of Plasmodium vivax (Grassi 



AND FeLETTI), in MaN AND THE AnOPHELINE MoSQUITO. 



number of daughter nuclei, around each of which the protoplasm 

 gathers, forming the sporoblasts, which are somewhat connected 

 together (Fig. 169). 



The nucleus of each sporoblast nov/ divides into several small 

 nuclei. These travel to the periphery, which grows out into a series 

 of small projections, each of which takes a chromatin particle with 

 it. Each of these projections is a sporozoite, so that each sporoblast 

 forms a large number of sporozoites, and leaves a residual mass of 



