^±4 



PLASMODROMATA AND SARCODINA 



red blood cells, but at times these are wanting. It may be vacuo- 

 lated, or it may be granular. 



The nucleus in the fresh specimen is usually difficult to see. It is 

 excentric, poor in chromatin, and easily altered by internal pressure. 

 It possesses a very delicate membrane, with a few peripherally 

 arranged grains of chromatin. 



In stained specimens there is rarely any differentiation of the 

 ectoplasm from the endoplasm. The cytoplasm may contain 

 vacuoles, erythrocytes, and perhaps the phagocyted nuclei of other 

 cells. The nucleus, unless distorted, is roundish, possesses a delicate 

 nuclear membrane, under which a thin band or a few grains of 

 chromatin may lie. The centre of thejnucleus is occupied by a 



Fig. 54. — Photomicrograph of the Living and Rapidly Moving 

 Loeschia histolytica Schaudinn, in the Young Trophozoite Stage of 

 Acute Dysentery, (x 1,500 Diameters.) 



(From the Journal of Tropical Medicine.) 



karyosome, which may contain a very minute centriole. The space 

 between the karyosome and the nuclear membrane sometimes shows 

 a delicate, poorly staining network, at the nodes of which lie fine 

 granules of chromatin. The cyclical changes described by Hart- 

 mann for the next stage are not visible. 



James has pointed out that when stained by Hastings' and 

 Giemsa's method the nucleus takes on a light blue colour, and con- 

 tains a delicate network of blue threads, and a number of fine red 

 coloured threads and bars scattered irregularly over this network, 

 composed of a substance which he calls erythrochromatin, to 

 distinguish it from the true chromatin. 



Old Trophozoite Phase. — -This is the phase so carefully described 



