458 



TR YPA NOSOMIDm 



parasitic origin. In view, however, of the work of E. H. Ross 

 and McDonagh on the organism of syphilis, it is possible that they 

 are in reality a stage in the development of T. pertenue. 



Comparison with T. pallidum.- — From the above description it 

 is evident that the framboesia organism is morphologically very 

 similar to that of syphilis. Blanchard, Martin, Prowazek, and 

 others seem to have been able to make out some slight morphological 

 differences between the two. Martin states that the framboesia 

 Treponema is even more slender and more difficult to stain than the 

 T. pallidum of Schaudinn. On the other hand, some authorities 

 consider it to be thicker. Rivas states that it has closer coils. 

 Prowazek, Levaditi, and Nattan-Larrier state that T. pertenue shows 

 less regularly shaped coils, and one extremity terminates in a loop 

 much more frequently than in T. pallidum. Moreover, according 

 to Levadi'-i and Nattan-Larrier, in fresh preparations T. pertenue 



Fig. 140. — Treponema per- Fig. 141.^ — Basophile Cell, with Chro 

 tenue Castellani. matin Dots, in a Case of Framboesia. 



dis;^lays whip-like lateral movements rather than translatory 

 ones. Russell and Archibald consider that T . pertenue is slightly 

 thicker than T. pallidum ; the distance from crest to crest of the 

 waves and the dip from the crest to the hollow is greater; the 

 parasite has greater tendency to curl up into a loop at one end. 

 Ranken states that the parasite does not show any corkscrew -like 

 motion, nor any progressive motion. We believe that the differentia- 

 tion of the two organisms, and in general of spirochaetes and Trypano- 

 somata, is to be based more on the results of the biological tests 

 than on slight morphological differences. The animal tests clearly 

 show that r. pertenue and T . pallidum are two different species, 

 inasmuch as monkeys immunized with T. pertenue do not become 

 immune for T . pallidum. 



Incidence of the T. pertenue in Framboesia Lesions. — ^The presence 

 of the Treponema is constant in the primary lesion and in the un- 

 broken papules of the general eruption. It may be found in the 



