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FUNGI IMPERFECT I 



ORDER III. HEMISPORALES Vuillemin, 1910. 



Definition.^ — Hyphales with the mycehum composed of abundant 

 hyphae, thin, but more than I micron in diameter, septate and 

 branched conidiophores ramified basally, each branch terminating 

 in a protoconidium, preceded by an annular construction produced 

 by a brown, rigid thickening of the wall. The protoconidium is 

 transformed completely or partially into deuteroconidia, but occa- 

 sionally it elongates, forming a new conidiophore, or puts out 

 branches which are capable of becoming conidiophores. 



Classification. — -There is only one genus, Hemispora Vuillemin, 

 1906. 



Genus Hemispora Vuillemin, 1906. 



Definition. — Mycelial filaments, thin, hyaline, septated, ramified. 

 Each conidiophore terminates into an ampuUiform structure (proto- 

 conidium), which later divides into several spore-like segments 

 (deuteroconidia). 



Hemispora stellata Vuillemin, 1906. 



Definition. — -Hemispora composed of white, sessile discs covered 

 with conidiophores, arranged like brown stars in relief on the 

 surface. Deuteroconidia subspherical, measuring 2 -6-3 '5 microns, 

 with a dark-coloured granular membrane except at the point of 

 attachment, sometimes elongated and barrel-shaped. Habitat, 

 parasitic on man and fungi. 



Remarks.— This species was first found in 1904 by Vuillemin, 

 growing on Aspergillus repens (De Bary, 1870). In 1909 Gougerot 

 and Caraven first found it parasitic in man, 

 and this has since been confirmed by other 

 cases described by Auvray, De Beurmann, 

 Clair and Gougerot, and by Thiry. So far it 

 has not been found in the tropics. 



Pathogenicity.— It is the cause of hemi- 

 sporosis, characterized by bony lesions and 

 cold abscesses simulating tertian syphilis, 

 tuberculosis, or sarcomata. 



Biology. — ^It grows well on sugar media at 

 ''fteui^v'."!"':^^'' the temperature of the room and when 

 (After Vuillemin ) separated m pure culture can be tested by 

 sero agglutination and complement fixation. 

 Typical colonies asteroid. 

 Treatment.^ — Iodide of potassium gives good result. 



Hemispora rugosa Castellani, 1910. 

 Synonym. — Monilia rugosa Castellani, 1910. 



Definition. — -Hemispora growing on all ordinary media, with a 

 crinkled surface without asteroid colonies. 



Remarks.^ — Isolated from cases of bronchitis and a case of tonsil- 

 litis by Castellani, and recently from a case of thrush by Pijper. 



