iii6 



FUNGI IMPERFECTI 



History. — Found by Chalmers and Archibald in a case of black 

 maduromycosis in Khartoum, Anglo-Egyptian Sudan. It occurred 

 in the sole of the foot of a native boy. 



Morphology — ^All cultures show septate branched hyphse, varying 

 in diameter from 2 -8-1 -4 microns, and increasing in very old 

 cultures, when all the hypfiae are dark, to 2-4 microns. At first the 

 hyphae are pale, but when older they become dark, being of a 

 greenish-black tinge. Thick walled, clear, or dark coloured. 

 Chlamydospores (14x11-3 microns) are present, and are especially 

 marked in the black masses on the surface of potato infusions and 

 nutrient gelatine. Aleuriospores are to be found acropleuro- 

 genously situated in the surface growth of old potato infusions. 



Cultures. — -The fungus grows well aerobically in glucose peptone 

 at 30° C, which is the optimum temperature. It also grows well 

 on maltose agar, on glycerine agar, glucose agar, and agar agar. It 

 does not liquefy inspissated blood serum or gelatine. It grows on 

 potato and carrot, but not on cheese or lard. It grew well on litmus 

 milk, but formed neither acid nor clot, though it produced a flaky 

 precipitate. On maltose agar the typical growth was in colour. 

 Ridgway's Standard Colour 'Dusky Drab,' and had a central 

 elevation surrounded by a depression, which separated it from a 

 grooved raised plateau which had a slight fringe. 



Habitat. — -So far it is only known in man, and all experiments with 

 grains or with cultures failed to infect monkeys, rabbits, or pigeons 

 intraperitoneally, subcutaneously, intramuscularly (with or without 

 a thorn), or into the anterior chamber of the eye. Attempts to find 

 a similar fungus on plants have so far failed. 



Pathogenicity. — 'It causes a variety of African Mack maduro- 

 mycosis. 



Glenospora semoni Chalmers and Archibald, 1917. 



Definition.— Glenospora closely resembhng G. kharfoumensis, 

 but differing markedly in cultural characters on maltose agar when 

 grown under exactly similar conditions. 



Remarks.— This fungus was isolated by Semon from a case of 

 black maduromycosis occurring in a native Indian soldier serving 

 in France. 



It is very like G. khartoumensis, but differs markedly in cultural 

 appearances, as maybe judged by a comparison of Figs. 6( i and 602 

 with Figs. 603 and 604. 



Pathogenicity.- — ^It causes a variety of Asian black maduromycosis. 



Genus Trichothecium Link, 1824. 



Fertile hyphae are erect, grouped together, each terminating in 

 an oval, pear-shaped, or globular conidium. The only species so 

 far observed in man is Trichothecium roseum, 



Type.^ — Trichothecium roseum (Persoon, 1801), emendavit 'Lmk, 

 1824, 



