I074 



FUNGI IMPERFECTI 



Found in abscesses in a woman by Busse. In the pus the fungus 

 presented itself in the shape of oval bodies, with a membrane 

 having a double contour. These elements were arranged in groups, 

 each group embedded in an amorphous substance and surrounded 

 by a capsule. Culturally the fungus showed only roundish budding 

 forms, no mycelium, no asci. Growth on solid media generally 

 white. Gelatine not liquefied. Glucose fermented. Pathogenic 

 to rabbits, white mice, and dogs. 



Cryptococcus lingusB-pilosae Lucet, 1901. 

 Synonym. — Sacchavomyces Ungues-piloses Lucet, 1901. 



Found by Lucet and others in cases of so-called ' black tongue.' It appears 

 on the surface of the hypertrophied ligual papillae in the shape of roundish 

 bodies, with double contour, 3 to 6 in diameter. Grows easily on sugar 



media. Often produces pellicle in sugar 



^_ media. Glucose and levulose fermented. 



Attempts to reproduce the disease have 

 failed. Guegen and Thaon believe that 

 this fungus becomes pathogenic only when 

 associated with Nocardia lingualis. 



The condition known under the name of 

 ' lingua nigra ' is caused in addition to the 

 above fungus, in some cases by Rhizopus 

 niger, in other cases by Nocardia lingualis. 



Cryptococcus plimmeri Constantin, 1901. 



Found by Plimmer in many cases of 

 cancer; is probably only a saprophyte. In 

 the tissues roundish bodies of various sizes, 

 4 to 40 ^ in diameter, are seen, occasionally 

 budding, and either free or intracellular. 

 Cultivation has succeeded only on one occasion, when it was found that it 

 produced a white growth on agar and other media. Action on gelatine and 

 other sugars have not been investigated. Cryptococcus plimmeri, according to 

 some authors, has been applied to cellular changes. 



Fi(5. 559. — Cryptococcus 

 piloses Lucet. 

 (After Lucet, from Brumpt.) 



Cryptococcus degenerans Vuillemin, 1896. 



Synonym. — Blastomyces vitrosimile degenerans Roncali, 1896. 



Found by Roncali and others in malignant tumours, sarcomata, and car- 

 cinomata. Easily grown; on potatoes it attains a much larger size than on 

 any other medium; on gelatine growth greyish-yellow. Sugar reactions 

 scarcely known. Does not ferment saccharose, but nothing definite known 

 about other sugars. Pathogenic for guinea-pigs. 



Cryptococcus corsellii Neveu-Lemaire, 1908. 



Found by Corselli and Frisco in a sarcoma of the mesenteric glands. The 

 fungus appeared in the tumours under the shape of black masses. It was 

 easily cultivated, and found pathogenic to guinea-pigs, rabbits, and dogs. 

 Sugar reactions unknown. 



Cryptococcus hessleri Rettger, 1904. 

 Synonym. — Blastomyces hessleri Rettger, 1904. 



Isolated by Hessler from a small tumour which developed on a patient 

 after a razor-cut. Easily cultivated, especially on alkaline media. Patho- 

 genic for the rabbit and guinea-pig. Sugar reactions unknown. 



