REFERENCES 



1925 



Though the white settlers regard it as a form of consumption, it is not 

 tubercular, and it does not appear to be associated with any malignant 

 growth. It does not correspond clinically with any known tabetic disease. 

 In one case seen in the earUer stages the pancreas was most affected . There 

 is a progressive enlargement of the liver and spleen, the abdomen becoming 

 considerably distended. All the fat disappears and the muscles atrophy, 

 but retain the power of movement. The appearance is quite characteristic — 

 extreme emaciation of the whole body, with a protruding abdomen. Ulti- 

 mately, through increasing weakness, walking becomes impossible, a serious 

 matter with these nomadic people, which may account for the fact that the 

 few cases of long duration which were observed had remained near white 

 settlements. The course of the disease is slow, but, so far as could be ascer- 

 tained, it always terminates fatally. Only one case was seen in a child, 

 who died within a year, whereas in the case of a woman who appeared to be 

 middle-aged it was said to have already lasted over two years. 



The cause of the disease is unknown. No parasite has been found in the 

 blood of patients examined in the endemic areas. 



Further investigation is necessary to see whether this disease is a type of 

 tropical splenomegaly {vide p. 1303). 



REFERENCES. 



The best general work is Biedl (191 3), ' The Internal Secretory Organs,* 

 London, while McCarrison (191 8), ' The Thyroid Gland/ is of very considerable 

 interest to the tropical practitioner, 



Castellani and Taylor (1917). British Medical Journal, December 29. 

 Castellani and Taylor (1919). British Medical Journal, February 15. 

 Castellani and Taylor (19 19). Journal of Tropical Medicine, July i. 



(Pentosuria in the Tropics.) 

 I^MiLE (1907). Journal of Tropical Medicine, p. 21. 



Glogner (1906). Archiv fiir Schiffs- u. Tropen-Hygiene, x. 17. (Rupture 

 of the Spleen.) 



Herzog (1908). Philippine Journal of Science, ii. i, 55. (Rupture of the 



Heart and of the Spleen.) 

 Macleod (1898). Journal of Tropical Medicine, i. 3. (Tropical Heart.) 

 Maxwell (1909). Transactions of the Society of Tropical Medicine, ii. 9. 



(Abscess of Spleen.) 



McCarrison (1909). Proceedings of the Royal Society, B, v. 81, No. B, 

 545. P- 31 (Goitre); (1913) The ^Etiology of Endemic Goitre. London. 

 Singer (1905). Journal of Tropical Medicine, viii. 17. (Goitre.) 

 Waters (191 7). Diabetes. 



