2254 



M ISCELLA NEO US DISEA SES 



with verruga sensu stricto (p. 1576), by Strong, Tyzzer, Brues, 

 Sellards and Gastiaburu. In framboesia the nodules have a mori- 

 form surface, and do not bleed so easily. 



Treatmeat. — Mercury and potassium iodide are useless. Basso- 

 witz recommends iron and arsenic internally, and externally the 

 injection into the base of the nodules of a few drops [of formahn, 

 or their excision, using the galvano-cautery. 



MULTIPLE PRURIGINOUS TUMOURS OF THE SKIN. 



Schamberg and Hirschler reported in 1905 two cases of multiple 

 tumours of the skin in negroes, associated with itching. The 

 tumours were sharply circumscribed nodules, from the size of a 

 small pea to a large hazel-nut, situated on the extremities. They 

 were of a blackish colour — the smaller smooth, the larger covered 

 with a horny epidermis. These tumours showed, on histological 

 examination, dilated vessels, cellular infiltration, with numerous 

 mast cells, and the formation of new collagenous fibres. The same 

 eruption was previously described in 1880 by Hardway in a white 

 woman. 



WEST INDIAN NODULES. 



This affection, which seems to be very similar to the preceding 

 one, has been described by Numa Rat in natives of the West 

 Indies, who often confuse it with Guinea-worm. The eruption 

 may attack any part of the body, and consists of subcutaneous 

 nodules varying from the size of a pea to that of a small nut. 

 There is extremely severe pruritus, and the natives destroy the 

 skin covering the nodules with caustics, and extract the nodules, 

 which appear yellowish-white and have a cartilaginous consistency. 



Histologically, according to Macleod, they consist mainly of 

 hypertrophied connective tissue made up of thickened collagen 

 bundles. The aetiology is unknown. 



MOSSY FOOT. 



Synonym. — Piemugoso. 



This affection is fairly common, according to Thomas, in the 

 region of the Amazon. 



The foot is covered with dense, warty, very vascular, painful 

 masses, as much as a half to three-quarters of an inch thick, which 

 may spread to the leg. 



The disease is very chronic, and probably of parasitic origin. 



The suggestion has been made by Cranston Low that it may be a type of 

 tuberculosis cutis verrucosa, and. by Da Matta that it may be a form of 

 leishmaniasis. 



BOTRYOMYCOSIS. 



Synonyms. — Botryomycosis Hominis, Granuloma Pyogenicum. 

 Definition. — A granulomatous condition characterized by the 

 presence of coccal bodies of various size and collected in clusters. 



