REFERENCES 



141 



Muscular work is especially dangerous, as under certain conditions 

 even a couple of sets of tennis may produce a temporary increase 

 of the bodily temperature, which may rise as high as ioi°-i02° F. 



If in addition to the deranged heat regulation there is added 

 cardiac weakness or lack of vaso-motor control, then heat-syncope 

 and not heat-stroke appears. 



The essential pathological change producing death from heat- 

 stroke is the partial coagulation of the globulin found in the cells 

 of the body. It is possible that this coagulation takes place first 

 in voluntary and cardiac muscles, thus leading to respiratory and 

 cardiac failure, while later marked changes are to be found in the 

 nerve cells, especially in the medulla, leading to chromatolysis. 



The clinical description of these diseases will be found in the 

 third part of this book, in Chapter LVI. 



REFERENCES. 



Pembrey and Ritchie (1913), 'General Pathoiogy,' London, contains a most 

 excellent article dealing with the above subjects under the heading Tempera- 

 ture. 



Duncan (1904). Journal of Tropical Medicine. (1908). Journal Royal Army 



Medical Corps, xi. 71. 

 Fayrer (1893). Davidson's Hygiene and Diseases of Warm Climates, p. 691. 



(1907). Allbutt and RoUeston's System of Medicine, II., ii. 771-782. 

 GiHON (1893). Twentieth-Century Practice of Medicine, iii. 253-285. (A 



good description of typical cases and a considerable literature.) 

 Giles (1906). British Medical Journal, ii. 596. 

 Haldane (1905). Journal of Hygiene, v. 494-513. 



Halliburton (1904). Bio-chemistry of Muscle and Nerve, pp. 107-115. 

 Hill (1906). Recent Advances in Physiology and Bio-chemistry, pp. 271- 

 274. 



HiRSCH. Handbook of Geographical and Historical Pathology, iii. 626-651. 



(A very full literature till about 1883.) 

 Manson (1904). Tropical Diseases, pp. 282-296. 



Rho (1907). Mense's Tropenkrankheiten (Italian translation). Also the 



new German edition, beginning in 191 3 and still coming out. 

 Sambon (1898). British Medical Journal, i. 744-748. (This account should 



be read, if possible.) 

 Sellards, Bovie and Brooks (1918). Journal of Medical Research, 



vol. XXX., No. 3. 

 Simpson (1908). Journal Royal Army Medical Corps, xi. 441. 

 Sutton (1909). Journal of Pathology, vol. xiii., pp. 62-73. Cambridge. 

 Wood (1887). Pepper's System of Medicine, v. 387-400. (A most excellent 



account, with many quotations.) 



