ORIENTAL SORE 



2169 



the disease was first claimed by Seriziat (1875) and by Tscherepkin 

 (1876). 



Tscherepkin states that by the people of Tashkent the disease 

 is called ' pascha-churdj , ' meaning ' fiy-bite/ Laveran thinks that 

 flies carry the virus on their feet and proboscis, and thus convey 

 infection. Schulgin and others beheve the disease to be conveyed 

 by mosquitoes. Ed. Sergent and Pressat have suggested that 

 some ' Phlebotomus ' may play a role in the transmission of the 

 disease, while Balfour and Thomson suggest that the bed-bug may 

 carry the infection. Fleas and lice have also been inculpated. 



The disease is inoculable from man to man, as is clearly proved 

 by the experiments of Marzinowsky and Wenyon. It is also auto- 

 inoculable. 



Marzinowsky inoculated himself with Oriental sore by putting inside the 

 bulla caused by an artificial burn on his hand some material (scraping) derived 

 from an Oriental sore. After ten days from the inoculation he began to feel 

 unwell and feverish, and suffered from headache and general debility. The 

 fever lasted two weeks. With the beginning of these general symptoms a 

 papule appeared at the seat of inoculation, which slowly developed into a 

 typical Oriental sore. Scrapings contained many parasites. Wenyon has 

 also inoculated himself, and he, too, presented fever before the skin lesion 

 appeared. The Bagdad Jews, according to Colvilli, inoculated their children 

 with the disease, as they thought that after having recovered once, there 

 was no danger of getting it again. 



Symptomatology. — After an incubation period varying from a 

 few days to some weeks or several months, during which attacks 

 of irregular fever often occur, one or several small pruriginous spots 

 appear on the skin of uncovered, parts of the body, not much dis- 



FiG. 852. — Oriental Sore. 



