226o 



MISCELLA NEO US DISEA SES 



may last for months, and if the patient has much walking to do, 

 may become very painful. 



Treatment. — Potassium iodide, mercury, and salvarsan are useless. 

 Rest and local applications of salicylic ointment or salicylic collodion 

 (ac. salicyl., 3i- ; collodion, gi.), or salicylic plasters induce a marked 

 improvement. 



JUXTA-ARTICULAR NODULES. 



Synonyms. — 'Enno,' Naride, Macgregor's nodules, Steiner's 

 tumours, Jeanselme's nodules. 



Historical and Geographical. — This affection was first :'briefly 

 described by Macgregor in 190 1 in New Guinea, who also suggested 

 a possible parasitic origin of it. It was later more fully studied by 

 Steiner in natives of Java and by Jeanselme in natives of Siam, where 

 it is known as ' enno.' Jeanselme introduced the very appropriate 

 term of ' juxta-articular nodules.' Fontoynont and Carougeau in 



Fig. 887. — Juxta-Articular Nodules. 



Madagascar jconsidered/ the cause of the [affection to be a fungus, 

 Nocardia carougeaui Brumpt, 1910. Cases have been 'observed in 

 Northern Africa by Gros and in Ceylon by us, also by Chalmers and 

 Archibald in the Sudan. The disease will probably be found ^to 

 occur in many other tropical and subtropical countries. 



>ffitiology. — Macgregor, Steiner, and Jeanselme considered the 

 nodules to be of parasitic origin, while Fontoynont and Carougeau 

 found a fungus which they believed to be the aetiological agent of 

 the condition. The description of this fungus — Nocardia carougeaui 



