256 



Col, Sir D. Bruce and others. 



[Dec. 18, 



on the 25th day. One of those in Column II had trypanosomes in the blood 

 the day after treatment and died that day. 



The results of the combined medication were thus scarcely superior to those 

 of the ethylantimonyl tartrate alone, for though there were fewer recurrences 

 when atoxyl was added, the mortality from poisoning was higher, so that only 

 two survived for two months as against six of those treated with antimony 

 alone. It is possible that by a more accurate adjustment of the two drugs 

 the advantages of diminished recurrence and low toxicity might be 

 combined. 



Amakebe : A Disease of Calves in Uganda. 



By Colonel Sir David Bruce, C.B., F.E.S., Army Medical Service ; 

 Captains A. E. Hamerton, D.S.O., and H. E. Bateman, Eoyal Army 

 Medical Corps ; and Captain F. P. Mackie, Indian Medical Service. 

 Sleeping Sickness Commission of the Koyal Society, 1908 — 09. 



(Received December 18, 1909, — Read January 20, 1910.) 



[Plate 10.] 



Introductory. 



Amakebe is the most important disease of cattle in Uganda. It attacks 

 the calves soon after they are born, and destroys more than half of them. 

 Among the native cattle the loss is reported to be as much as 75 per cent., 

 but, with careful nursing and hand-feeding, this mortality may be reduced to 

 between 20 and 30 per cent. This is an enormous toll to pay, and renders 

 the breeding of cattle in Uganda for dairy purposes, or, indeed, for any 

 purpose, very up-hill work. 



Little up to the present has been written as to the nature and causation 

 of Amakebe. It has been described as a trypanosome disease, but this 

 evidently on insufficient knowledge. 



Didribution in Uganda. 



Aiiiakclie api)earH to occur all over the Kingdoms of Uganda, Unyoro, 

 Ankolc, and Busoga. Lieutenant A. D. Fraser, Royal Army Medical Corps, 

 the medical officer lately in charge of the Sleeping Sickness Camp, Sesse, 

 roi)ortH, however, tli(! curious fact that it does not occur among the cattle on 

 the Se.sse Islands. Mr. C. W. llatterslcy also informs the Coniuiission that 



