262 



Col. Sir D. Bruce and others. 



[Dec. 18, 



Experiment 1635. — To study Amakebe in the Calf. 

 The foljowing chart represents the course of the temperature — 



Chart 5. — Experiment 1635. Temperature Curve in a Case of Amakebe ending Fatally. 



From these foregoing cases and the j)ost-mortcm examinations, it will be 

 seen that amakebe is an acute disease of calves, and that the main features of 

 \he post-mortem are signs of intense anaemia, petechise of serous membranes, 

 infiltration, of jelly-like material into omentum, anterior mediastinum, base of 

 heart, etc., oedema of lungs, swelling and softening of spleen, hsemorrhagic 

 infarcts into lungs, spleen and kidneys, and sometimes ulceration of the 

 mucous membrane of the stomach. 



Piroplasms usually fotcnd in the Blood of Uganda Cattle. 



When the blood of cattle in Uganda is examined microscopically, two 

 parasites are always to be found, though usually in very small numbers. One 

 of these can readily be recognised as Firoplasma higemimim from its large 

 size and the characteristic appearance of the two pear-shaped bodies (Plate 10, 

 fig. 1). It may, however, also appear as irregularly-shaped, amoeboid forms, 

 especially in the spleen (Date 10, fig. 1). The other parasite is much smaller 

 in size, and is usually seen in the form of a small rod or ring (Plate 10, fig. 2). 

 Both these parasites are inoculable, and appear in tlie blood of calves without 

 giving ri.se to any marked disturbance. 



Have either of them any connection with Amakebe ? 



The following experiments go to show that tliey liave not : — 



Experiment 556. 



To ascertain the effect on a Susceptible Calf of the Injection of Blood containing the 

 Small liod and Iling- shaped Piroplasm. ' Will it give rise to Amakebe ? 



Feb. 22, 1009. — This calf was born last night. To-day the mother was cleared of ticks by 

 liaii(l-j)iikiiig, and then c()nii)let(!ly smeared with a mixture of paraffin and 

 cyllin, and mother and calf then jjlaced in a tick-free enclosme. 

 „ 26.— Injected this calf with 6 c.c. blood from calf, Experiment 430, whose blood 

 contains the small rod and ring-sh.aped ])ir(>plasm. 



