296 



Dr. M. Haaland. The Contrast in the [Jan. 17, 



mouse-embryo skin ; a fourth with mouse-embryo skin ground at a temperature 

 of about 0° as above. Fourteen days later all these mice, with controls 

 corresponding, were inoculated with 0-01 c.c. of carcinoma " 63." Fig. 1 

 shows the result of this experiment as observed on the 10th, 17th, 24th, and 

 31st day after the inoculation. In the control mice there are 17 tumours 

 in 18 mice, i.e. 94 per cent. The mice treated with fresh embryo-emulsion 



1-18 CONTROL 



NORMAL Mice. 

 av.wt.I5.gr 



19-23 TREATED WITH 

 TOTAL MOUSE EMBRYO 



I9-3T TREATED WITH 

 TOTAL MOUSE EMBRYO 





12/1 



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12 DAYS 



PREVIOUSLY. 



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j ALL MICE INOCUL ATEO 



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. WITH 0 



38-51 TREATED WITH 

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 FRESH 

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52-62 TREATED WITH 

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 FROZEN ^^I_^'aN0 GROUND 

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Fifi. 1.- -Experiment 63/24 T, showing the innmmising efl'ecl of jircliniinai y tieatnient of 

 mice with normal tis.suen and the aholition of this ett'ect after disintegration of the 

 tissues by freezing and grinding. The numbers represent individual mice treated 

 as stated at the top of each column. The silhouettes represent to scale the sizes of 

 the tumours obtained in each animal at the dates stated, 10, 17, 24, and 31 d^s 

 after inoculation. Negative results are rejiresented by — . " 



are completely protected, whereas the mice of the third column, treated with 

 ground embryo, developed tumours in each case, ■!.>■. 100 per cent. The som(!- 

 what slower growth of tlie tumours in the third column, as compared with 

 the controls, may lie attrilmted to an infection, which killed several mice in 

 tlie same cage, as shown on the chart. The mice treated with fresh skin gave 

 one tiunoiir in 14 mice (/.''. 7 ]ioi- cent.), whereas the corresponding l)atch 



