476 Col. Sir D, Bruce and others. Trypanosome [May 13, 



It may therefore be concluded that I'ryjpanosoma pecorum sets up a rapid 

 and fatal disease in cattle. 



. Disease set up in Goats and Sheep hy Trypanosoma pecorxim. 



The number of cases of this disease in goats and sheep which came under 

 observation is too small to draw any conclusions from. At Mpumu the 

 goats and sheep were not satisfactory experimental animals, as many of them 

 died from some unknown cause. It was thought that as these animals 

 usually lived in the valleys, and ' were often housed in their owner's hut 

 during the night, the exposure on the top of the hill had a bad influence. 

 One sheep was still alive after 168 days, and it is probable that most of the 

 goats and sheep would have lived much longer if they had been kept under 

 more favourable conditions. 



Disease set up in the Smaller Laboratory Animals. 



It is not necessary to describe in detail the action of Trypanosoma pecorum 

 on the monkey, dog, and smaller laboratory animals, as a reference to the 

 table will show the average periods of incubation and duration. It will be 

 seen that this is a fairly rapid and fatal disease in the dog, white rat, and 

 mouse. In the monkey the average duration is about two and a-half months. 



The Carrier of Trypanosoma. Pecorum. 



Glossina;. — From experiments made in the laboratory at Mpumu it seems 

 probable that Glossina p>alpalis is capable of acting as a carrier of this 

 trypanosome. Four experiments were made with ordinary wild Lake-shore 

 flies, and of these one was successful. Four were also made with laboratory- 

 bred flies, and one again came off. The latter experiment, however, with 

 lal)oratory-bred flies was not free from doubt ; but from the other, which 

 seemed free from doubt, it appears that Trypanosoma pecorum can develop in 

 Glossina palpalis and infect a licalthy animal after a period of 21 days. 

 More observations are required. It may be noted that in no instance did 

 Trypanosoma pecorum appear in the blood of animals upon which freshly- 

 caught Lake-shore tsetse flies had been fed. These flies were found to be 

 naturally iiifctcted with Trypanosoma ganibicnse andi Trypanosoma vivax. This 

 is an argument, thougli a small one, that Glossina palimlis is not the common 

 or chief carrier of T'rypaiiosoma jx'corum. 



Tahanidcc. — There is some circumstantial evidence available to show that 

 Trypanosoma pecorum is caiiicd by the Tabariida: In tlui valleys round 

 Mpumu Hill, HO far as we are aware, there are no tsetse flies at any time of 



