254 Inoculation for Pleiiro-Pneumonia in Cattle. 



learned bj the following note received froiii Mr. Pjatt on 

 December 17th: — 



"On Monday last, December 13, I went to Ruddington, and, in accordance 

 with your directions, I re-inoculated twelve of the cows. Not tiie slightest 

 effect was produced by the former operation, except in two cases. In one, 

 No. 19, I found the tail swollen and very sore, with a scab about the size of 

 a shilling covering the place of inoculation. I have seen this cow daily since 

 Monday, and, although she appears to be perfectly well in health, the tail is now 

 much more inflamed, and the wound looking so badly, that I fear in a few 

 days the tail will slough. The re-inoculations were made from a highly 

 diseased lung, and it seems to me they will all take, as the tails are now a little 

 swollen and very sore when pressed. 



(Signed) " Henry Pyatt." 



It will be se6n from this letter that the fluid used for the 

 re-inoculations was the product of a more advanced stage of 

 Pleuro-pneumonia ; to this and also to the deep punctures made 

 by Mr. Pyatt, the marked inflammation that speedily followed, or 

 the success of the inoculation as it is designated, is to be attri- 

 buted. On the same day that these twelve animals were re- 

 inoculated two others were operated on, and on December 19th 

 two more. These latter two were inoculated with sero-purulent 

 fluid obtained from the inoculated places of other cows, being 

 what is technically called " a first remove. The animals bore 

 the respective numbers of 10 and 21, these being the marks 

 stamped upon their horns on purchase, and necessary to be made 

 mention of for the purpose of identification. 



On the 23rd of December we paid a second visit to Ruddington. 

 The local effects of the operation, consisting of ordinary inflame 

 motion^ advancing with greater or less rapidity to suppuration, were 

 marked in all ; but, comparatively speaking, they were slight in 

 seven out of the twelve original cases. The two animals operated 

 on the same day with the twelve, December 13th, presented a 

 similar condition of the parts, as did also the two inoculated hy 

 the first remove. 



We selected seven of the most satisfactory cases from out of the 

 fourteen inoculated direct with fluid from the lung, to give trial 

 to re-inoculation. On four of these the re-inoculation produced 

 morbid action equally as great as the original inoculation ; on the 

 others it failed. This fact, which is one of the first importance, 

 we shall have again to allude to, and therefore we refrain from 

 commenting upon it in this place. Between the 23rd and the 

 close of the month four more cows were inoculated by " the first 

 remove,^^ and it was observed that more speedy action followed 

 this method than that of direct inoculation with the exuded 

 serum of the lung. 



During the month of December Pleuro-pneumonia continued 



