Inoculation fur Pleuro-P neumonia in Cattle. 



2o7 



Eight cows lost their tails from mortification, induced by the 

 operation. Evidence of this untoward result was generally 

 afforded about eight or ten days subsequent to the inoculation. 



One animal, the young bull previously mentioned, died from 

 the inoculation. The mortification which succeeded extended 

 upwards, affecting the perineum, rectum, and adjacent parts. His 

 death occurred on the twenty-first day of the operation. The 

 lungs and viscera of the chest were found free from disease. 



This freedom from disease of the lungs will be hereafter com- 

 mented on ; it is referred to by the Dutch Commissioners, who, 

 also, in another of their conclusions have truly observed that 

 *' when the violent action occurs, and extends to the more vital 

 parts, affecting the Avhole system, its progress can as little be 

 prevented and checked as the disease in general can be cured." 



The two inoculated cows which were lost in February by 

 Pleuro-pneumonia were attacked the one three weeks and three 

 days and the other three weeks and five days subsequent to in- 

 oculation. The effects of the operation are described as being 

 slight. 



The three cows w^hich were attacked in ±^^ay with Pleuro- 

 pneumonia were inoculated, one on January 13th, another on the 

 20th, and the third on the 21st of the same month. The latter 

 two were both observed to be ill on May 5th, being fifteen weeks 

 after the inoculation. The third cow, inoculated on January 13th, 

 was taken ill on May 22nd, and disposed of two days afterv.ards, 

 being eighteen weeks and three days subsequent to her inocula- 

 tion. In two of the animals Mr. Pyatt reports that the effects 

 of the inoculation were comparatively/ slight, but yet deemed at 

 the time to be suiiicient to protect them. 



We noAV proceed to some experiments which were made in the 

 Royal \ eterinary Colle£:e on animals also furnished for that pur- 

 pose by Mr. Paget. On our fi.rst visit to Ruddington in Novem- 

 ber it was arranged to send six cows to London ; the animals 

 accordingly vrere forv.'arded by rail, and arrived safelv at the 

 College on December 10th. 



Four days afterwards, it being considered that they had re- 

 covered from the fatigue of their journey, we inoculated three of 

 them in the usual place and somewhat in the usual manner, 

 cautiously making the pimctures just through the skin of the tail. 

 JVo effects folloiced, and the inoculation was therefore repeated 

 in the same careful manner, at an interval of eight days, that is, 

 on December 22nd. This inoculation also failed, and, instead of 

 having recourse forthwith to deeper punctures rour/hly made 

 zcith a bad-cutting instruments^' we determined to try punctures^ 

 punctures even still more superficially made, and also scratches 

 of the cuticle. This was done on all the cows on December 30th ; 



VOL. XIV. s 



