380 



Messrs. Parkes and Wollowicz on the Effect of [May 19, 



Putting together the evidence derived from the pulse as felt by the 

 finger, from the state of the cutaneous vessels, and from the sphygmo- 

 graphic tracings, it seems fair to conclude that the chief effects of alcohol 

 on the circulation in health are on the ventricles (the rapidity with which 

 contractions are accomplished being greatly increased), and on the capil- 

 laries (which are dilated and allow blood to pass more freely through 

 them). The valuable observations of Dr. Anstie have shown that in many 

 febrile cases, when alcohol is acting usefully, the arterial tension is in- 

 creased ; while in other cases, when there is narcotism, the tension is 

 lowered. In this healthy man the effect of either small or large doses on 

 the arterial tension is not perhaps well marked. 



Action on the Urine. 



Elimination of water by the kidneys. 



Days 



1 



2 

 3 

 4 

 5 

 6 

 7 

 8 

 9 

 10 

 11 

 12 

 13 

 14 

 15 

 16 

 17 

 18 

 19 

 20 



21 



22 



23 



24 



25 

 2G 



Fluid taken in twenty-four hours in food and drink. 



72J fluid ounces of water, or 2059 c. c 



72^ fluid ounces of water, or 2059 c. c 



72^ fluid ounces of water, or 2059 c. c 



72^ fluid ounces of water, or 2059 c. c 



72^ fluid ounces of water, or 2059 c. c 



72| fluid ounces of water, or 2059 c. c 



72^ fluid ounces of water, or 2059 c. c 



72 J fluid ounces of water, or 2059 c. c 



71'5 fluid ounces, or 2030 c. c, and 1 fluid ounce of alcohol ... 

 70 5 fluid ounces, or 2002 c. c, and 2 fluid ounces of alcohol... 

 69 fluid ounces, or 1959 c. c, and 4 fluid ounces of alcohol ... 

 67 fluid ounces, or 1902 c. c, and 6 fluid ounces of alcohol ... 

 65.5 fluid ounces, or 1860 c. c, and 8 fluid ounces of alcohol... 

 65*5 fluid ounces, or 1860 c. c, and 8 fluid ounces of alcohol... 



72-| fluid ounces of water, or 2059 c. c 



72£ fluid ounces of water, or 2059 c. c 



72^ fluid ounces of water, or 2059 c. c 



72^ fluid ounces of water, or 2059 c. c 



72-g fluid ounces of water, or 2059 c. c 



72£ fluid ounces of water, or 2059 c. c 



66 - 5 fluid ounces of water, or 1880 c. c, and 6 ounces of alco- 

 holic brandy 



f 66-5 fluid ounces of water, or 1880 c. c, and 6 ounces of alco- 



\ holic brandy 



" >5 fluid ounces of water, or 1880 c. c, and 6 ounces of alco- 

 holic brandy 



72£ fluid ounces, or 2059 c. c 



72£ fluid ounces, or 2059 c. c 



72i fluid ounces, or 2059 c. c 



addition to this the tracing shows the special characters of the pulsus celer, the descrip- 

 tion of which in my book, page 14, seems still correct (Handbook of the Sphygmograph, 

 1867). 



" (4) The celerity or shortness of the expansile movement I understand to signify 

 that the left ventricle performs its contraction within a shorter period, and therefore 

 uses more force within a given time than in its natural state k 



" (5) I do not see any reason for supposing that the arterial pressure is increased.'' 



