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ON PATHOLOGICAL STATES IN EVOLUTION. 



environment to which it reacts. The factors which did the 

 work are working now. 



To recapitulate the tentative conclusions arrived at, it may be 

 suggested that — - 



1. Mechanical reaction to stress is a general law of all tissues. 



2. Morbid conditions in many cases give rise to repair which 

 becomes physiological. 



3. Such repairs lead to new functions, new stresses, further 

 morbid states and further repair. 



4. These factors are some of the main causes of specific and 

 generic differences. 



5. In all probability transmission of changes caused in the 

 way indicated does take place by a morphogenetic reply in utero 

 to increased functional stresses. 



6. As it is a narrow view to assume that pathology in all cases 

 tends to death, the study of pathology and general physiology 

 should be part of the preparation of the biologist. 



