121 



Case v. 



Light bay stallion, 4 years old, observed in July, '88. 



Clinical rc7iiarks: — According to anamnesis the first change 

 appeared in January '88, at the xyphoid region, whence it spread 

 over the breast, scrotum, penis, back, &c. Stains praesens was 

 as follows ; — extremely meagre ; temperature 39°C., respiration 

 17, pulse 65 and irregular. Nodes and ulcers, characteristic of 

 Japanese farcy, over the body, especially on the front, lips, 

 axillary region, anterior extremities down to phalanges, back, 

 chest, right side of haunch, xyphoid region, scrotum, penis, and 

 the thigh of both posterior legs ; the right tarsus uniformly 

 swollen. The Schneiderian membrane on the left side ex- 

 tensively ulcerated, while on the right side it showed only a 

 few ulcers : destroyed and dissected on July 23rd. 



Postmortem appearance : — Many nodes found in the subcutis 

 more especially of shoulders and of the internal surface of 

 posterior extremities. In the latter, the intermuscular tissue 

 and periost were also affected. Lymphatic glands of intermaxil- 

 lary, inguinal, pubic and femoral region were swollen. The left 

 testicle and epididymis contained plenty of characteristic herds 

 of pea to hen egg size ; many of the same herds were also found 

 in the right epididymis and spermatic cord, and a few in the 

 proper testicle. Both nose cavities extensively ulcerated ; three 

 ulcers of hazelnut size in the frontal sinus. Liternal organs free 

 from changes. 



Microscopical appearance was the same as in the preceding 

 case. 



Lioculation: — Guinea pigs No. 7 and 8 were inoculated, on 

 June 22nd with nasal discharge. No. 9—12, on June 23rd with 

 metastatic herds of testicle, and No. 13 and 14, with ulcerative 

 tissue of nose. Results were as follows ; — 



No. 7, inoc. with nasal discharge. On the 3rd. day redness 

 and swelling appeared at the locus itioculationis ; on the 5th day, 

 preputium and scrotum swollen. 9th day, an ulcer appeared on 

 the scrotum ; the left plica gland swollen and hard, 2 cm. 

 in diameter. The right plica gland also swollen, and it 



