124 



nose. On July i8th (23rd day) nasal discharge ceased, and there 

 was no lesion in the Schneiderian membrane : on the chest, a 

 thumb-sized induration still persisting. July 27th (32nd day), at 

 the upper part of the subcutaneous induration, an egg-sized ulcer 

 appeared with profuse granulation. The ulcer gradually increas- 

 ed in size until July 3 1 st ; afterwards it became smaller day by day, 

 and on August 8th it was 3 cm. long and I cm. broad, yielding 

 a little yellowish semitransi^arent fluid. On August lOth the 

 horse was destroyed and dissected: internal organs were quite 

 healthy. 



Bay mare No. 2, 4 years old, inoculated on July 25th, in 

 the same way as No. i. Local reaction also nearly similar, 

 and skin wound completely healed on July 14th. No special 

 changes in the nose. 



Case vii. 



Black bay stallion, 4 years old, observ'ed in June, 18S8. 



Clijiical remarks: — Condition meagre ; characteristic nodes 

 and ulcers at the right cervical region, both shoulders and 

 anterior extremities down to fetlock, both posterior extremities, 

 sacral region, &c. Destroyed and dissected on June 28th. 



Postmortem appearance : — Besides cutaneous and sub- 

 cutaneous changes, there were some ulcerative nodules in the 

 nose cavity and a few nodules in the epididymis; lymphatic 

 glands normal. 



hioculation of 5 guinea pigs (No. 18-22), on June 28th, with 

 ulcerative tissue of nose and metastatic nodules of epididymis. 

 Besides local inflammatory changes, in 4 guinea pigs, more or 

 less swelling of plica gland appeared, but this swelling afterwards 

 subsided. Two of the animals died on July 15th from acute 

 gastroenteritis ; the internal organs free from farcy changes. 



Case viii. 



Light bay stallion, 4 years old, observed in June '88. 



Clinical appearance : — According to ^;/^r;«w^« first symptoms 

 of farcy appeared in the previous December, on the right 

 shoulder, whence it extended over the abdominal wall, 

 both posterior extremities, and at last over the left anterior 

 extremity. Nasal discharge was first noticed in May (1888). 



