138 



Inoculation of 4 guinea pigs (No. 56-59) : No. 56, inoculated 

 witli the ulcerative tissue of nose, showed swelling and ulcera- 

 tion in loco and swelling of the inguinal gland. No. 57, 

 inoculated with the same substance, showed only a local 

 swelling. No. 58, inoculated with the content of farcy, died on 

 the 4th day from malignant ocdem. No. 69, inoculated with the 

 content of farcy boil, showed local suppuration for a long time, 

 but gradually recovered. 



In No. 58 we found, postmortem, a small abscess in the 

 epididymis, and from the content wc obtained a pure culture of 

 bacillus mallei. 



Cask xxii. 



Old summer black stallion, observed in April, 1892. 



Clinical remarks : — This horse was purchased for experi- 

 mental purposes. When he arrived he had farcy on the head, 

 shoulder, neck, back, posterior extremities, &c., here and there 

 ulcers being confluent to an extended superficial ulceration 

 covered with thin bloody fluid. Condition bad and lame in 

 the right posterior extrcmit)'. 



Twice mallein was injected. Afterwards the process made 

 more rapid progression ; purulent discharge took place from 

 the nose, and ulcers appeared on both sides of septnm nasi ; 

 the intermaxillary glands not swollen. Death on June 13th, 

 1892. 



Postmortem appearance : — Numerous nodules, abscesses, and 

 ulcers scattered over the \\'hole bod)-. As in the foregoing 

 case, the nodules mostly situated in the cutis ; in those 

 places, where the skin was destroyed — shoulder, axillary region, 

 posterior extremities, &c., the morbid process was propagated 

 in the subcutis along the course of lymphatics, which were swollen 

 to a varicose chain, forming here and there nodes or abscesses 

 of pea to wal-nut size ; the content of abscess consisted of pus of 

 mucilaginous consistency. The cutaneous ulcers on transection 

 funnel-like, their bottom indurated and greyish white. In the ex- 

 tremities nodes distinctly prominent and polypous, whose apex 

 being in a state of caseous metamorphosis. On the head, ulcers 

 reached the periost. Subcutis of both posterior extremities showed 



