HS 



inguinal region, the left posterior extremity and the perineum. 

 Nothing abnormal in the lymphatic gland or nose cavity. This 

 horse received one injection of mallcin, and was treated after- 

 wards by surgical operations. The treatment was successful, and 

 the animal apparently recovered. 



On Oct. 10, '93, the horse was inoculated subcutancously witli 

 pure culture of B. obtained from Prof. Schiitaes laboratory. 



The following changes were observed in succession ; local 

 swelling and induration, formation of nodes, oily purulent 

 discharge from inoculation wound, tlie diffuse swelling and 

 eruptions of farcy boils and ulcers on the posterior extremity, 

 similar eruptions on the right side of neck, sternal region, left 

 flank, and on tlie internal thigli, swelling of the right anterior 

 extremity ; eruptions in the skin of traciieal region and of the 

 right posterior extremity. From these foci the morbid process 

 quickly spread over the neighboring parts. Then appeared 

 nasal discharge, which was even bloody. Wound secretion of 

 loctis iuociilationis and nasal discharge were quite characteristic 

 of genuine glanders, and we could easily demonstrate bacillus 

 mallei in these disciiargcs ; while nodes and ulcers in otiier 

 regions of the body were prominent, and had the appearance 

 of Japanese farcy, and in these eruptions we found numerous 

 saccharomyccs. The horse died on November 21, '93; and was 

 dissected on the 22. 



Postmortem appearance : — Extreme emaciation : mucous 

 discharge from both nostrils. Farcy boils and ulcers on the 

 head, the inferior cervical, left praescapular and sternal region 

 the inferior and lateral abdominal wall, the thigh of the left 

 posterior e.xtrcmiy, the scrotum, and the heel of the right 

 anterior and left posterior extremities : the subcutis of the last 

 mentioned extremities sluiwed elephantiac thickening. The 

 subcutaneous abscesses, which were abundantly found, contained 

 thick yellowish pus characteristic of Japanese farcy ; in some 

 of them, the content was a little thimier and mucilaginous. 

 Ul cers showed infiltrated border, but were not polypous as com- 

 monly met with in Japanese farcy. In the nose cavity, es- 

 pecially on tlie right side, numerous ulcers, pea-linseed in size ; 

 they were mostly liollow with infiltrated bottom and border, 

 and the larger ulcers with pale irregular granulations : the 

 Eustachian valves and larynx showed a number of smaller 



