152 



case XIX was pure glanders with pulinonar}' complication. 



Ill II cases (xill-XXXni) saccJiaroinyccs were actually 

 demonstrated, but it was not possible to find the presence of 

 bacillus mallei; in these cases the clinical and postmortal 

 appearances were quite characteristic of Japanese farcy. In 

 cases I and IV-xxn sacchannnyccs were not directly examined ; 

 we have, however, stated the presence of the latter in the 

 alcoholic specimen of morbid tissues collected from these cases. 

 There is hence no doubt that all our cases, except the above 

 3 and cases II and III, which were not examined for saccliaro- 

 myces, were those of saccJiaroinycotic farcy. In cases III and 

 XXVIII the subcutaneous nodes were in process of healing 

 without surgical operations. 



Case XXVII was an example of mixed infection of genuine 

 and saccJiayomycotic farcy. It is interesting to note that, both 

 groups of symptoms were combined. The anatomical characters 

 of cutaneous and subcutaneous nodes and ulcers were quite 

 the same as in Japanese farc}-. The following were the chief 

 deviations from the latte r : — 



1. Acute course. 



2. Nasal ulcers were hollow and not fungoid. 



3. Purulent discharge from nose was oily and mucila- 



ginous. 



4. Distinct pulmonary lesion. 



5. Histologicall}' the nasal and pulmonary Jierd con- 



sisted of a typical granulation tissue, while in 

 Japanese farcj^ the tissue elements or leucoc}'tes 

 are in an earlj^ stage destroyed hy the invasion 

 of microbes. 



It is also interesting to observe that, B. mallei which was 

 inoculated, became causa iiicitans for the recidivum of saccharo- 

 mycosis and that, in the further course of disease the number of 

 saccharomyces decreased and finally disappeared in most of the 

 abscesses. Ver}^ likely the recidivum of saccharomycosis was 

 not due to the favorable influence of bacillus mallei, but to the 

 favorable condition of the anatomical changes prepared by the 

 latter. To the question whether symbiosis of both microbes is 

 possible or impossible, our observations were not sufficient to 

 enable us to give a definite answer. Nevertheless we may con- 

 sider this case as a mixed infection. Cases IX and XXI too may 



