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formation of abscess and ulceration in loco and the swelling of the 

 next lymphatic gland (plica gland) and, in exceptional cases, of the 

 testicles. In fact the reaction was dependent on : i, the mass 

 of morbid tissue inoculated and, 2, the purity of the substance. 

 The larger the mass introduced in the subcutis, the stronger was 

 the local reaction. The reaction was stronger and more con- 

 spicuous in those animals, which had been inoculated with 

 ulcerative tissue from exposed parts, skin and nose, than in 

 those, which received morbid tissue from fresh cadavers and 

 from internal organs, as the testicles. Certainly different septic 

 microorganisms, which may easily cleave to organic matter, 

 have played the chief part in producing local reactions. Old 

 cadavers of horses are soon loaded with them, and the latter 

 often interfered with the result of inoculation. In the usual 

 course there was local swelling, suppuration or formation of 

 abscess, ulceration, and the swelling of the next lymphatic 

 gland, the latter being in proportion to the intensity of local 

 ulceration. All these changes were not so characteristic of 

 ninlleus, and mostly terminated in recovery. For easier 

 reference we give the result of inoculation in the following 

 table : — 



