167 



changes caused by the irritation of morbid products aspired or 

 absofbeci by blood vessels and lymphatics. Most pulmonary 

 changes, for instance, would not be the result of direct irritation 

 of saccJiaromyccs, but due to the irritation of morbid materials 

 or pyogenic bacteria aspired from the ulcerative surface of the 

 nose. The same view can equally hold good with other internal 

 changi s. The morbid products absorbed by blood vessels may 

 occasion metastasis or irritate any excretory apparatus, especial- 

 ly the kidneys, through which they are eliminated from the 

 body. 



On tJie gtiieyal state 0/ health: — In slighter cases of Jap. farcy, 

 when the process is localized in a small circumference, there is 

 no evidence of general disturbance ; tiie patient is active, has a 

 good appetite, and no febrile symptoms ; even in advanced cases 

 the animal can do its ordinary work. When the nose is affected, 

 or when cutaneous changes are far advanced, the condition of 

 the animal quickly falls, emaciation sets in, and the result is 

 cachexia and death. In most advanced cases the appetite is more 

 or less disturbed, and the temperature is always above 39-^ C. — 

 hectic fever. 



The disease is always of long continuance, and may last for 

 months or even years. Acute cases, in the true sense of the 

 meaning, never occur. The disease assumes an acute character 

 when it is spread over a large part of the skin and of the mucous 

 membrane of tubus respirator ins. Exact details as to the dura- 

 tion are wanting. 



Termination and possibility of treatment : — -As the disease is 

 progressive, so in the natural course it generally terminates in 

 death. Complete recovery is possible by radical operation, but 

 only in slighter cases, in which the process is still localized in 

 the skin. We must, however, remind the fact that, cure was also 

 possible without any surgical operation (Case XXVIII), in which 

 case the subcutaneous nodules were successfully encapsuled by 

 connective tissue. In order to ascertain whether the cure, as 

 commonly spoken of, is apparent or complete, we have dissected 

 a number of horses, which had recovered from farcy. The anam- 

 nesis and status praesens were as follows : — 



I. Black stallion, 7 years old ; dissected on July 2nd, 

 1888. A namnesis : affected in the spring, 1887 

 treated and cured. Status praesens: many cica- 



