Un Bromalbumin and its Behaviour to IVIicrobes. 



BV 



O. Loew and S. Takabayashi. 



Bromalbumin has recently been recommended for medical 

 purposes. As it contains bromine organically bound, it seems to 

 be better adapted than the combination of peptone with hydro- 

 bromic acid, whose therapeutical properties were studied by 

 Rosenthal'' but found not to differ essentially from those of 

 potassium bromide. 



Bromalbumin was first prepared by one of us^'^' in the year 

 1885 by mixing finely powdered and well dried albumin (loog.) 

 with bromine (50CC. or about 150 g.) and leaving the mixture to 

 itself for about four weeks. Hereby only a very small quantity 

 of hydrogen bromide becomes liberated and the albumin is 

 gradually transformed into a thick semi-liquid mass, which, after 

 well washing with water, retains a portion of losely bound 

 bromine so obstinately, that primary sodium sulphite had to be 



(1) Zeitschr. physiol. Chem.^^, 227. 



(2) U. Loew, Journ. f. prakt. Chem. j/, 138. 



