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PATHOLOGY: FLEXNER AND A MOSS Proc. N. A. & 
also of the mouse and a bacillus of the enteritidis group with which to con- 
duct experiments, and the reports he has already published, in spite of 
quite fundamental differences of procedure, are readily comparable with 
those we have obtained. 
As a matter of practical importance perhaps the epidemic diseases 
affecting the respiratory tract may be more important than those in which 
the portal of entry into the body of the infectious microbe is by way of the 
digestive tube. The latter class has indeed been subjected to far greater 
control by sanitary and other measures than the former. But in 
endeavoring to work out the underlying principles ultimately to be assem- 
bled into the "laws" of epidemics, information from many sources will be 
required. It is part of our object, however, to report later on experimental 
epidemiological studies now in progress with a disease of laboratory animals 
in which the infecting bacillus thrives on the respiratory mucous mem- 
brane. It is obvious that the two chief factors involved in epidemio- 
logical investigations, namely the host and the microbe, are both highly 
intricate. Any comprehensive study will include both, and to the extent 
to which it is enlightening will account for the effects of the fluctuation o£ 
one on the response of the other, the two conditions having been corre- 
lated providing the data on which our ultimate understanding of epi- 
demics will come to rest. 
ij. Hygiene, 19, 1921 (349). 
