580 
CHEMISTRY: E. C. FRANKLIN 
to another even though the parents are deprived of the tumors by an 
operation. 
I am gratefully indebted to Professor Morgan and Doctor Bridges for 
helpful suggestions. 
Conclusions. — 1. A non-lethal tumor appeared as a mutation in the 
lethal tumor strain. 
2. The locus of the gene of the new tumor is close to that of the 
dichaete in the third chromosome. 
3. The tumor may occur in any segment of the larva but seems to 
occur more often in the twelfth and thirteenth segments. 
4. The cells of the tumor are rounded or polygonal in shape and show 
the presence of pigment. 
5. Ingrowth of tumor cells into the imaginal discs of the appendages 
checks the development of the parts. 
6. Young tumors were inserted into larvae of normal strains. Five 
per cent survived the operation, completed metamorphosis and carried 
the inserted tumor into the adult fly. 
METALLIC SALTS OF PYRROL, INDOL AND CARBAZOL 
By Edward C. Franklin 
Department of Chemistry, Leland Stanford University 
Communicated, October 20, 1919 
The ammono acids, that is to say, the acids of the ammonia system 
of acids, bases and salts,^ are derivatives of ammonia in which one or 
two hydrogen atoms of the ammonia molecule are replaced by negative 
groups. A number of examples of compounds so related to ammonia 
are nitramide or nitrosyl amide, NO2NH2; acetamide or acetyl amide, 
CH3CONH2; phthalimide or phthalylimide, C6H4\^^yNH; benzene- 
sulfonnitramide or nitrosyl benzenesulfonyl imide, C6H5SO2NHNO2; 
methylnitramine or methyl nitrosyl imide; acetanilide or phenyl acetyl 
imide; trini tramline, C6H2(N02)3NH2; cyanamide, CNNH2; urea, CO- 
(NH2)2 etc., etc. 
These substances are true acids ranging in acidity from benzenesul- 
fonnitramide, which approaches the ordinary mineral acids in strength, 
through phthalimide and methyl nitramine, which are well known to 
possess weak acid properties, to acetamide and urea which are not 
