34 Prot 
XVIII. PROTOZOA. 
[1904] 
globular. Billet (26). — Observations pointing to an endoglobular phase 
in the life-history of Trypanosome (not unlike Piroplasm(x donooani)y 
Moore (243). 
Myxosporidiosis : — 
Thelohania moenadis does not appear to injure to any extent the in- 
fected Carcinus. though the host's muscles may be infested with it, Perez 
(263). 
Severe epidemics of " Drehkrankheit " (characterized by spasmodic 
irregular movement) in young rainbow-trout, due to Lentospora cerehmlis ; 
relation of the parasites to the host's tissue [see also ill. c.l, Plehn 
(2G9). 
Relation between the host's tissue and the parasitic invasion in the case 
of Glugea stephani ; " pseudocysts " the result of a condition of diffuse 
infiltration. Woodcock (361). 
Protozoa and other diseases: — 
The development of the Amoeba of tropical dysentery {Entamoeha 
histolytica) shews that it is distinct from E. coli, Lesage (202), — Amceha 
coll and its relation to so-called tropical dysentery and hepatic abscess, 
Verdun (350). — Amoebic dysentery in Ceylon, Castellani (62). 
Cysts of Trichomonas intestinalis and Megastoma entericum in human 
f^)eces, Ucke (346). 
Cytoryctes variolce certainly seems to be the cause of small-pox ; relation 
of the parasite to the cells and nuclei of the lesions in this disease fully 
described. Calkins (58j. — The " vaccine " bodies are phases of an organism 
very closely allied to Cytoryctes variolce if not identical ; the difference 
between the effects in the two cases (small-pox and vaccinia) is apparently 
due to the fact that in the latter the parasite does not become intranuclear, 
Tyzzer (345). 
Inoculation of Monkeys {Rhoesus and Macacus) with small-pox virus ; 
occurrence of diff'erent forms of the parasite {Cytoryctes) which are 
described, Magrath & Brinckerhoff (218). 
Photomicrographs of the small-pox parasite, shewing its relation to the 
cells and nuclei, Councilman, Magrath & Brinckerhoff (78). 
The supposed Protozoan parasite of vaccinia (cow-pox and horse-pox) — 
[most unsuitably termed " Plasmodium " vaccime] — and its relation to the 
malady discussed, Bosc (32 & 33). 
DE KoRT^ (161) describes what he considers as the Protozoan parasite 
of small-pox and vaccinia, terming it " Amoeba variolce^ 
SiEGEL (318) considers the cause of vaccinia to be a peculiar spore- 
forming parasite of Sporozoan attinity, readily found in the kidney-tissue. 
Bosc (29-31) maintains the parasitic nature of the inclusions in 
cancerous cells, regarding them as Protozoa. He compares these organ- 
isms \T\ with the bodies he has found in " clavelee," small-pox, vaccinia, etc. 
ScHUBERG (308) points out that Feinberg [Zool. Rec. 1903 \109)] has 
mistaken for " intestinal cysts filled with Coccidia '"' what are really 
Cysticerci of a tape-worm ! It would follow, therefore, that much reliance 
cannot be placed upon the Protozoan nature of his cancer-inclusions. 
The " one and only true cancer })arasite has again revealed itself, this 
time to ScHULLER (310), who regards it as a Protozoan and gives numerous 
unconvincing figures of it. 
According to Luzzani (214) a Protozoan parasite has been observed in 
a case of hydrophobia, and is considered to be the cause. 
D. Reproduction. 
Comparative review of the diflferent modes of reproduction in the 
Protozoa, and their classification, Hartmann (135). 
