GENETICS: R. PEARL 
383 
Plymouth Rock 9 . There were produced 234 chicks from matings 
wherein one or both parents were treated. 
The following reasoning has been used in devising a numerical ex- 
pression of the dosage, so far as concerns the progeny. Two germ 
cells, a sperm and an ovum, unite to form the zygote of each progeny 
individual. It is proposed to designate as the 'total germ dosage index' 
the total number of days during which the two gametes making the 
offspring zygote have been exposed to alcoholic influence while sojourn- 
ing in the body of the treated individuals. 
The total germ dosage index for the Fi progeny in these experiments 
ranges from 130 days to 354 days, with the matings for the different 
substances used well scattered over the range. A summarized state- 
ment of the effects on the progeny is given in Table 11. 
TABLE n 
' Showing in Summary Form the Effect of Continued Administration of Alcohol 
(Ethyl and Methyl) and Ether by the Inhalation Method, upon the Progeny 
CHARACTER STXJDIED 
OFFSPRING OF 
NET 
RESULT 
ON 
ALCOHOL 
OFF- 
SPRING 
Treated 
X 
un- 
treated 
9 9 
Treated 
X 
treated 
9 9 
All 
treated 
parents 
Un- 
treated 
controls 
1. 
Mean germ dosage index 
137.8 
299.0 
210.35 
0 
2. 
Percentage of infertile eggs (i.e., eggs in which no 
25.2 
59.2 
41.7 
25.3 
3a. 
Percentage of embryos dying in shell 
36.6 
26.9 
33.3 
42.2 
+ 
3b. 
Percentage of fertile eggs (i.e., rygotes) which 
hatched 
63.0 
72.3 
66.7 
57.8 
+ 
4. 
Percentage of all eggs which hatched 
47.1 
29.4 
38.6 
44.4 
5. 
21.1 
10.6 
17.6 
36.9 
+ 
6. 
5.9 
13.6 
10.3 
15.3 
+ 
7. 
Sex ratio: per cent cf 
48.9 
45.5 
47.7 
50.0 
0 
8. 
Mean hatching weight per bird, males 
34.91 
36.97 
34.24 
+ 
9. 
35.04 
37.17 
34.73 
+ 
10. 
Mean adult weight per bird, males 
2669 
2815 
2392 
11. 
Mean adult weight per bird, females 
2020 
2063 
1928 
+ 
12. 
Percentage of weak or deformed chicks 
0.7 
0 
0.4 
1.0 
+ 
13. 
AbnormaHties of MendeHan inheritance 
0 
0 
0 
0 
0 
An examination of this table shows that out of 12 dif event characters 
for which we have exact quantitative data, the of spring of treated parents 
taken as a group are superior to the offspring of untreated parents in 8 
characters. The offspring of untreated parents are superior to those of 
the alcoholists in respect of but two characters, and these are characters 
which are quite highly correlated with each other and really should be 
